Lycopene: Chemistry, Biosynthesis, Health Benefits and Nutraceutical Applications

Singh, Shubhi; Gaur, Smriti

doi:10.1007/978-981-15-2361-8_11

Cited by 2 publications

(2 citation statements)

References 43 publications

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“…Lycopene supplementation boosted mitochondrial gene expression and lowered mitochondrial dysfunction [ 6 , 172 ]. Lycopene and tomato products were found to decrease the total cholesterol and low-density lipoprotein cholesterol (LDL-C) in clinical investigations [ 173 , 174 , 175 ]. In healthy postmenopausal women, lycopene supplementation can decrease total and LDL cholesterol [ 176 ].…”

Section: Lycopene In Cardiovascular Diseases (Cvds)mentioning

confidence: 99%

Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases

et al. 2022

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Lycopene is a bioactive red pigment found in plants, especially in red fruits and vegetables, including tomato, pink guava, papaya, pink grapefruit, and watermelon. Several research reports have advocated its positive impact on human health and physiology. For humans, lycopene is an essential substance obtained from dietary sources to fulfil the body requirements. The production of reactive oxygen species (ROS) causing oxidative stress and downstream complications include one of the major health concerns worldwide. In recent years, oxidative stress and its counter strategies have attracted biomedical research in order to manage the emerging health issues. Lycopene has been reported to directly interact with ROS, which can help to prevent chronic diseases, including diabetes and neurodegenerative and cardiovascular diseases. In this context, the present review article was written to provide an accumulative account of protective and ameliorative effects of lycopene on coronary artery disease (CAD) and hypertension, which are the leading causes of death worldwide. Lycopene is a potent antioxidant that fights ROS and, subsequently, complications. It reduces blood pressure via inhibiting the angiotensin-converting enzyme and regulating nitrous oxide bioavailability. It plays an important role in lowering of LDL (low-density lipoproteins) and improving HDL (high-density lipoproteins) levels to minimize atherosclerosis, which protects the onset of coronary artery disease and hypertension. Various studies have advocated that lycopene exhibited a combating competence in the treatment of these diseases. Owing to all the antioxidant, anti-diabetic, and anti-hypertensive properties, lycopene provides a potential nutraceutical with a protective and curing ability against coronary artery disease and hypertension.

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Section: Lycopene In Cardiovascular Diseases (Cvds)mentioning

confidence: 99%

Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases

et al. 2022

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“…Clinical studies have shown that lycopene and tomato products lower total cholesterol and low-density lipoprotein cholesterol (LDL-C) [89]. Supplementing with lycopene can help healthy post-menopausal women, and might lower LDL and total cholesterol.…”

Section: Cardiovascular Diseasesmentioning

confidence: 99%

Overview of the Potential Beneficial Effects of Carotenoids on Consumer Health and Well-Being

et al. 2023

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Well-known experimental research demonstrates that oxidative stress is the leading cause of the onset and progression of major human health disorders such as cardiovascular, neurological, metabolic, and cancer diseases. A high concentration of reactive oxygen species (ROS) and nitrogen species leads to damage of proteins, lipids, and DNA associated with susceptibility to chronic human degenerative disorders. Biological and pharmaceutical investigations have recently focused on exploring both oxidative stress and its defense mechanisms to manage health disorders. Therefore, in recent years there has been considerable interest in bioactive food plant compounds as naturally occurring antioxidant sources able to prevent, reverse, and/or reduce susceptibility to chronic disease. To contribute to this research aim, herein, we reviewed the beneficial effects of carotenoids on human health. Carotenoids are bioactive compounds widely existing in natural fruits and vegetables. Increasing research has confirmed that carotenoids have various biological activities, such as antioxidant, anti-tumor, anti-diabetic, anti-aging, and anti-inflammatory activities. This paper presents an overview of the latest research progress on the biochemistry and preventative and therapeutic benefits of carotenoids, particularly lycopene, in promoting human health. This review could be a starting point for improving the research and investigation of carotenoids as possible ingredients of functional health foods and nutraceuticals in the fields of healthy products, cosmetics, medicine, and the chemical industry.

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Lycopene: Chemistry, Biosynthesis, Health Benefits and Nutraceutical Applications

Cited by 2 publications

References 43 publications

Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases

Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases

Overview of the Potential Beneficial Effects of Carotenoids on Consumer Health and Well-Being

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