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Introduction: The spread of carbapenem-resistant Acinetobacter baumannii (CRAB) is difficult to control especially in the hospitals due to the successful mobilization and evolution of the genetic elements harboring the resistant determinants. The study was conducted to examine the distribution of aminoglycosides, tetracycline, and sulfonamide-resistant determinants among CRAB isolates that carry the blaOXA-23 gene. Methodology: For a total of 160 CRAB strains isolated at tertiary care hospitals of Pakistan that mainly carried blaOXA-23 gene were included in the study to evaluate the assortment of antibiotic resistance genes. Results: The susceptibility rates of CRAB for other than beta-lactam drugs were 2.5% for both ciprofloxacin and aminoglycosides and 18% and 25% for sulfonamides and tetracyclines, respectively. Polymyxin B (MIC90, 1 g/mL) Colistin (MIC90, 1 g/mL) and Tigecycline (MIC90, 2 g/mL) were most active against these extensively drug-resistant CRAB isolates. The isolates were found to possess various genes mainly the tetB and sul2 for tetracycline and sulfonamide but the genes conferring resistance to aminoglycosides were varied with various combinations. Conclusion: Despite the CRAB clones containing blaOXA-23 have been previously reported in Pakistani hospitals, the screening of genetic determinants responsible for other antimicrobial agents is crucial for developing an effective surveillance and mitigation system for infection management.

Vegetables supply various minerals, vitamins, dietary fibers along with important phytochemicals that plays a major contribution in our balance diets and nutrition. Each vegetable contain a unique amount of various nutrients that are strongly linked with the protection of different health diseases. Eggplant (Solanum melongena L.) is a nonwoody annual plant with purple to white flowers along with enlarged lobed leaves with bushy foliage that grows with maximum height of 120cm. Eggplant is mainly grown for vegetables and medicinal purposes. The phytochemical analysis of eggplant shows that it is the rich source of various essential compounds aspartic acid, tropane, flavonoids, lanosterol, gramisterol, steroid alkaloids, glycoalkaloids, histidine, nasunin, oxalic acid, solasodine, ascorbic acid and tryptophan that are present in fruits and leaves. It also contains low calories and high moisture contents. These compounds were found helpful in the cure of various diseases like cancer, anti-inflammatory, anti-asthmatic, anti-platelet hypo-lipidemic, and hypotensive etc. Today most modern scientific techniques are available to cure different various health problems but still majority of population across the globe depends upon the traditional herbal medicines and practices. This review mainly explains nutritional content, medicinal and health benefits of S. melongena