Lutein: More than just a filter for blue light

Kijlstra, Aize; Tian, Yuan; Kelly, Elton R.; Berendschot, Tos T. J. M.

doi:10.1016/j.preteyeres.2012.03.002

Cited by 295 publications

(258 citation statements)

References 129 publications

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“…The uses of lutein extracts in the formulation of nutritional supplements for the prevention of age-related macular degeneration (AMD) have become increasingly popular over the past few years (Kijlstra et al, 2012). Synthetic methods have been developed for the production of lutein; however, the cost of production cannot compete with that of lutein isolation from marigold extracts (Fernández-Sevilla et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant activities and lutein content of 11 marigold cultivars (Tagetes spp.) grown in Thailand

Ingkasupart¹,

Manochai²,

Song³

et al. 2015

Food Sci. Technol (Campinas)

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Antioxidant activities and total phenolic content (TPC) were analyzed in ethanol extracts of 11 marigold cultivars grown in Thailand. Antioxidant activity assays performed in this study were the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical cation scavenging activity, ferric ion reducing antioxidant power (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, oxygen radical absorbance activity (DRAC), and superoxide anion radical scavenging activity (SRSA) assays. 'Dptiva Drange' showed the best activity in the DRAC assay and in % SRSA, as well as the highest content of lutein (20.59 mg), gallic acid (25.77 mg), and quercetin (12.61 mg) per gram dry marigold petal among the 11 cultivars. Furthermore, 'Dptiva Drange' showed the highest lutein yield per plant, as compared to other cultivars. In contrast, 'Rodeo Gold' showed the highest activity by ABTS testing (0.92 mmol of trolox/g dry sample), as well as an 89.90% inhibition of DPPH. Lutein content showed a positive correlation with TPC and all antioxidant activity assays. In conclusion, 'Dptiva Drange' and 'Rodeo Gold' could be utilized as a good lutein source for functional food products and cosmetics.Keywords: marigold cultivars; antioxidant activity; phytochemical.Practical Application: Two marigold cultivars grown in Thailand showed high antioxidant activity among 11 cultivars tested.

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Section: Introductionmentioning

confidence: 99%

Antioxidant activities and lutein content of 11 marigold cultivars (Tagetes spp.) grown in Thailand

Ingkasupart¹,

Manochai²,

Song³

et al. 2015

Food Sci. Technol (Campinas)

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“…In addition to their antioxidant activity, these carotenoids hold great potential for improving macular pigment density (26) and, therefore, help filtering blue light. Thus, HDL is studied for its possible key role in protecting against AMD (27) .…”

Section: Discussionmentioning

confidence: 99%

Association of high-density lipoprotein and apolipoprotein E genetic variants with age-related macular degeneration

Cezario¹,

Calastri²,

Oliveira³

et al. 2015

Arquivos Brasileiros De Oftalmologia

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“…The main isomer of lutein presents in plants and vegetables is its Trans form, but during processing it results in significant isomer changes. [8] The chemical formula of lutein is C 40 H 56 O 2 and the molecular weight is 568.88.…”

Section: Structure and Chemistry Of Luteinmentioning

confidence: 99%

Lutein – The Less Explored Carotenoid

Hirdyani¹

2017

WJPR

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Lutein and zeaxanthin are xanthophyll carotenoids found particularly in dark-green leafy vegetables and in egg yolks. They are widely distributed in tissues and are the principal carotenoids in the eye lens and macular region of the retina. Epidemiologic studies depicts an inverse relationship between xanthophyll intake and Retinitis Pigmentosa (RP), cataract and Age-Related Macular Degeneration (ARMD) thus suggesting a protective role of these compounds in the eye. Some observational studies have also shown these xanthophylls may help reduce the risk of certain types of cancer and diabetes. It is also known to have beneficial effects on skin health. Emerging studies suggest as well a potential contribution of lutein and zeaxanthin to the prevention of various cardiovascular diseases too. The use of lutein as a nutritional supplement has been explored in recent years. It is used as a major pharmaceutical but its application as a nutraceutical still needs to be emphasised upon as its industrial application will be very promising in near future. Lutein is a promising biologically active component in the food industry.

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Lutein: More than just a filter for blue light

Cited by 295 publications

References 129 publications

Antioxidant activities and lutein content of 11 marigold cultivars (Tagetes spp.) grown in Thailand

Antioxidant activities and lutein content of 11 marigold cultivars (Tagetes spp.) grown in Thailand

Association of high-density lipoprotein and apolipoprotein E genetic variants with age-related macular degeneration

Lutein – The Less Explored Carotenoid

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