Lung metastasectomy in adenoid cystic carcinoma (ACC) of salivary gland

Locati, Laura D.; Guzzo, Marco; Bossi, Paolo; Massone, Paolo P. Brega; Conti, Bárbara; Fumagalli, Elena; Bareggi, Claudia; Cantù, Giulio; Licitra, Lisa

doi:10.1016/j.oraloncology.2005.04.014

Cited by 61 publications

(69 citation statements)

References 15 publications

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“…There have been a few reports on the surgical resection of pulmonary metastases from head and neck cancer. [50][51][52] Those head and neck cancers included squamous cell carcinoma of the larynx, pharynx, or oral cavity, adenoid cystic carcinoma, and thyroid cancer. It has been consistently suggested that pulmonary metastasectomy for squamous cell carcinoma of the head and neck is benefi cial for prolonging survival, with 5-year survival rates of 30%-40% reported.…”

Section: Head and Neck Cancermentioning

confidence: 99%

Current status of pulmonary metastasectomy from primary epithelial tumors

2009

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The resection of pulmonary metastases can prolong the survival of selected patients and its therapeutic value is now accepted. The criteria for eligibility have also evolved. We reviewed the recent literature on pulmonary metastasectomy for various epithelial primary tumors and tried to establish better prognostic indicators for its surgical application. In addition to the welldefined requisites for pulmonary metastasectomy, other requirements include the absence of mediastinal lymph node involvement, a limited number of pulmonary metastatic lesions, a long disease-free interval, small metastasis, and no elevation of tumor markers, although the clinical importance of each factor varies among the primary tumors. On the other hand, with the development of video-assisted thoracoscopic surgery (VATS) and advances in thoracic imaging technology, VATS metastasectomy might become an accepted treatment for metastatic nodules located in the periphery of the lung, which can be easily removed by a wedge resection. Repeat surgery is also possible during follow-up after VATS.

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Section: Head and Neck Cancermentioning

confidence: 99%

Current status of pulmonary metastasectomy from primary epithelial tumors

2009

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“…Distant metastases occur in 25-50% of the individuals, particularly to the lungs and bone. Also, they are more common and unpredictable [7].…”

Section: Discussionmentioning

confidence: 99%

Adenoid Cystic Carcinoma of the Buccal Mucosa: A Case Report with Review of Literature

Santhanam¹,

Aravindhan

2014

JCDR

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A 48-year-old female patient presented with complaint of a swelling in the left cheek, in relation to left upper back tooth region. The swelling was present since 1 year and it had arisen as a small one, after extraction of a decayed left upper back tooth. History revealed that the swelling had increased gradually to attain its present size and that it was not associated with pain. There was no relevant medical, surgical or personal history. On extra oral examination, there was no evidence of erythema, ulceration or ecchymosis. Single left submandibular lymph node that was mobile, firm, non-tender and of size 0.5x0.5 cm, was palpable. Intra oral examination revealed a single localized dome shaped swelling of size 2x3 cm in the left buccal mucosa, in relation to 27 region, which extended posteriorly till the faucial pillars of the tonsils [Table/ Fig-1]. The mucosa which overlay the swelling was erythematous in nature and its surface was smooth. There was no surface discharge, the swelling was firm in consistency and it was nontender. The swelling was fixed to the underlying tissue and the area which surrounded the swelling, appeared to be normal. Clinical differential diagnosis included benign mesenchymal neoplasms, reactive or inflammatory conditions of minor salivary glands, benign or low grade malignant tumours of salivary gland origin, and metastatic tumour deposits of distant site. An orthopantomograph was taken and it revealed no bony changes in the maxilla or the mandible. Lesion was excised in toto, it was Dentistry Section aBstRaCt Minor salivary gland neoplasms of the buccal mucosa are relatively uncommon. Adenoid cystic carcinoma (ACC), a well-defined entity, occurs most of the times in the parotid, submandibular glands and palate, as far as the intraoral site is concerned. Adenoid cystic carcinoma tends to have an indolent, extended clinical course with wide local infiltration and late distant metastases. We are presenting a case of an adenoid cystic carcinoma of the buccal mucosa in a 48-year-old female patient.[table/ Fig-1]: Clinical picture depicting a mass of the buccal mucosa

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“…Because of its slow course, 5-year survival is about 70% but falls to 30-60 and 15-50% at 10 and 15 years, respectively (Kokemueller et al 2004). Following histologic conWrmation of a recurrence, patients with lung metastases only should be considered for metastasectomy (Locati et al 2005). Those with local disease or metastases not amenable to resection or radiotherapy are often treated with chemotherapy.…”

Section: Discussionmentioning

confidence: 99%