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2015
DOI: 10.1007/s00240-015-0839-4
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Lowering urinary oxalate excretion to decrease calcium oxalate stone disease

Abstract: Dietary modifications should be considered as a first line approach in the treatment of idiopathic calcium oxalate nephrolithiasis. The amounts of oxalate and calcium consumed in the diet are significant factors in the development of the disease due to their impact on urinary oxalate excretion. There are a number of strategies that can be employed to reduce oxalate excretion. The consumption of oxalate-rich foods should be avoided and calcium intake adjusted to 1000–1200 mg/day. To encourage compliance it shou… Show more

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Cited by 51 publications
(41 citation statements)
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“…Normally, intestinal oxalate absorption is low and highly variable (around 10%-15%) [56]. In individuals without malabsorption syndrome, bowel oxalate uptake may increase only when intestinal ionized Ca is reduced, often due to high dietary consumption of phytate (calcium-binding molecule) and/or low-calcium diet [57].…”
Section: Oxalatementioning
confidence: 99%
“…Normally, intestinal oxalate absorption is low and highly variable (around 10%-15%) [56]. In individuals without malabsorption syndrome, bowel oxalate uptake may increase only when intestinal ionized Ca is reduced, often due to high dietary consumption of phytate (calcium-binding molecule) and/or low-calcium diet [57].…”
Section: Oxalatementioning
confidence: 99%
“…Containing high amount of calcium, dairy products reduce stone formation risk by decreasing intestinal absorption of oxalate [29]. However, there are several studies which suggest that there is not a correlation between dietary calcium intake and stone formation [30,31].…”
Section: Discussionmentioning
confidence: 99%
“…A low oxalate diet, potassium citrate supplementation, and calcium supplementation are beneficial. Calcium therapy for hyperoxaluria deceases oxalate absorption linearly with increasing dietary calcium dose of up to 1200 mg/d …”
Section: Discussionmentioning
confidence: 99%