Low-power laser biostimulation enhances nerve repair after end-to-side neurorrhaphy: a double-blind randomized study in the rat median nerve model

Gigo-Benato, Davilene; Geuna, Stefano; Rodrigues, Antônio de Castro; Tos, Pierluigi; Fornaro, Michele; Boux, E.; Battiston, Bruno; Giacobini-Robecchi, Maria G.

doi:10.1007/s10103-004-0300-3

Cited by 126 publications

(95 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Such data corroborate the results from other authors who have used LILT during 12 days of tissue repair processes and verified responses from the fibroblastic cells and collagen molecules to the treatment 7,8,[19][20][21][22][23][24][25][26][27][28] . The types of activation ways proposed for the laser, take into account its action over the chromophores situated at the mitochondrias and cell membranes.…”

Section: Discussionsupporting

confidence: 90%

Influência de diferentes comprimentos de onda da laserterapia de baixa intensidade na regeneração tendínea do rato após tenotomia

Erb

Rodrigues

Taciro

et al. 2007

Rev. bras. fisioter.

View full text Add to dashboard Cite

Objective: The aim of this study was to compare the effect of the low level laser therapy in the organization of the collagen fibers with 3 J/cm² of dose in two wavelengths (670nm and 904nm) and in the combination of both on the tissue repair of the calcaneus tendon. Methods: We used 37 female Wistar rats divided in 5 groups which had been submitted to the total tenotomy. Group GA (n= 8) was submitted to the laser irradiation in λ= 904nm, GaAS, pulsated emission, peak power 15W and dose of 3J/ cm², group GB (n= 8) was submitted to laser irradiation λ= 670nm AlGaInP diode, continuous emission, power 30 mW and dose 3J/cm², group GAB (n= 8) was submitted to association of both of lasers and group GCL (n= 7) which the calcaneum tendon was submitted to placebo treatment. The group GP (n= 6) was a standard group without lesion and treatment. The animals received 12 sessions of lasertherapy and submitted to euthanasia on 14 th day after surgery. The tendons were submitted to histological procedure and were analyzed to evaluate the optic retardation (in nm) for the birefringence measurement. Results: The statistic analysis showed that the irradiated groups have higher values of optic retardation statistically significant than placebo group (p= 0,00001). It indicates that all the treated groups show better organization of collagen fibers in the longitudinal axis of the tendon, evidencing better quality in the tissue repair. The group GAB was that shown best results (p= 0,00001) when compared to another groups.

show abstract

Section: Discussionsupporting

confidence: 90%

Influência de diferentes comprimentos de onda da laserterapia de baixa intensidade na regeneração tendínea do rato após tenotomia

Erb

Rodrigues

Taciro

et al. 2007

Rev. bras. fisioter.

View full text Add to dashboard Cite

show abstract

“…Gigo-Benato et al (20) utilizaram duas diferentes formas (contínua e pulsada) e comprimentos de onda (808 e 905 nm), de laser na forma pontual, e analisaram seus efeitos sobre a neurorrafia término-lateral. Para o laser 808 nm a dose foi 29 J/cm 2 , e para 905 nm a dose foi 40 J/cm 2 .…”

Section: Discussionunclassified

Uso do laser, 670 nm, no quadro álgico de ratos submetidos à modelo experimental de ciatalgia

Cunha¹,

Moesch

Mallmann

et al. 2008

Rev Bras Med Esporte

View full text Add to dashboard Cite

A ciatalgia deve-se a compressão do nervo isquiático em algum ponto de seu trajeto, e seu tratamento consiste em solucionar a causa da compressão nervosa, seja por tratamento cirúrgico ou conservador. Alguns recursos fisioterapêuticos atuam basicamente na redução dos sintomas ocasionados por este distúrbio. O objetivo deste estudo foi verificar a eficácia do laser 670 nm, em duas diferentes densidades de energia, na redução do quadro álgico, em ratos submetidos a modelo experimental de ciatalgia. Foram utilizados 18 ratos, divididos em 3 grupos: G1 (n=6) submetidos à ciatalgia e simulado o tratamento (grupo placebo), G2 (n=6) submetido à ciatalgia e tratados com laser 2 J/cm², G3 (n=6) submetidos à ciatalgia e irradiados com laser 4 J/cm². O nervo isquiático do membro posterior direito dos animais foi exposto e compressão com fio catgut em 4 pontos ao redor do nervo foi realizada. No 3° dia pós-operatório, iniciou-se o tratamento com laser na região do procedimento cirúrgico do membro posterior direito durante 10 dias consecutivos. Verificou-se por meio da marcha, o tempo em que o membro permanecia no ar nos períodos: anterior à ciatalgia, pré e pós-tratamento. Os resultados demonstraram que o laser não foi eficaz na redução do quadro álgico, porém com 4 J/cm² houve efeito positivo, sem restabelecimento completo da funcionalidade.Palavras-chave: laser de baixa potência, dor, nervo isquiático. ABSTRACTSciatica is caused by the sciatic nerve compression in some point of its course, and its treatment consists of solving the nervous compression cause, either by surgical or conservative treatment. Some physiotherapeutic resources act basically in the reduction of the symptoms caused by this disturbance. The aim of this study was to verify the effectiveness of the laser 670 nm, in two different energy densities, in the pain reduction, in rats submitted to a sciatica experimental model. Eighteen rats, divided in 3 groups were used: G1 (n=6) submitted to sciatica and simulated treatment (placebo group), G2 (n=6) submitted to sciatica and treated with laser 2 J/cm², G3 (n=6) submitted to sciatica and irradiated with laser 4 J/cm². The hamstring nerve of the animals' right hind limb was exposed and compression with catgut thread in 4 points of the nerve was performed. On the 3rd post-operation day, the treatment was begun with laser in the surgical procedure area of the right hind limb for 10 days. The time during which the limb remained on the air was verified through gait in the following periods: previous to the sciatica, before and after treatment. The results have demonstrated that the laser was not effective in the pain reduction; however, with 4 J/cm² there was positive effect, without complete functionality reestablishment.Keywords: low level laser therapy, pain, sciatic nerve. INTRODUÇÃOA ciatalgia pode ser considerada como uma síndrome dolorosa referida, na qual a dor é percebida na extremidade do membro inferior, na ausência de qualquer distúrbio local (1) . Este quadro deve-se a compressão do nervo isquiático...

show abstract

“…They found that this approach could enhance the growth and healing of the injured nerve 20) . However, it is difficult to apply to CTS patients.…”

Section: Discussionmentioning

confidence: 99%

Low-level Laser Treatment Relieves Pain and Neurological Symptoms in Patients with Carpal Tunnel Syndrome

Jiang

Chang

et al. 2011

J Phys Ther Sci

View full text Add to dashboard Cite

Abstract.[Purpose] This placebo-controlled study investigated the therapeutic effects of low-level laser treatment (LLLT) on the transverse carpal ligament in carpal tunnel syndrome (CTS). [Subjects and Methods] Idiopathic CTS patients were recruited and were randomly assigned to two groups. The laser group (n = 45) received laser treatment (10 Hz, 60 mW, 9.7 J/cm 2 , 830 nm), and the placebo group (n = 42) received sham laser treatment. The visual analog scale (VAS), Boston Questionnaire scale, neurological symptoms and nerve conduction study (NCS) were conducted before, immediately after and 5 weeks after the treatment.[Results] After LLLT, there was statistically significant decrease in VAS in the laser group (p<0.05). Especially, the effect of LLLT on pain alleviation in the mild CTS group continued after five weeks. Regarding the Boston Questionnaire scale neurological symptoms and NCS, only mild CTS patients in the laser group showed statistically significant improvements after treatment (p<0.05).[Conclusions] LLLT with 830 nm diode lasers on the transverse carpal ligament had verifiable therapeutic effects for mild CTS patients.

show abstract

Low-power laser biostimulation enhances nerve repair after end-to-side neurorrhaphy: a double-blind randomized study in the rat median nerve model

Cited by 126 publications

References 48 publications

Influência de diferentes comprimentos de onda da laserterapia de baixa intensidade na regeneração tendínea do rato após tenotomia

Influência de diferentes comprimentos de onda da laserterapia de baixa intensidade na regeneração tendínea do rato após tenotomia

Uso do laser, 670 nm, no quadro álgico de ratos submetidos à modelo experimental de ciatalgia

Low-level Laser Treatment Relieves Pain and Neurological Symptoms in Patients with Carpal Tunnel Syndrome

Contact Info

Product

Resources

About