Low-dielectric-constant polyimide aerogel composite films with low water uptake

Kim, Jin‐Young; Kwon, Jinuk; Kim, Myeong-Soo; Do, Jeonguk; Lee, Daero; Han, Haksoo

doi:10.1038/pj.2016.37

Cited by 148 publications

(99 citation statements)

References 31 publications

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“…Nonetheless, comparison with previous more complex model results suggests that the outcomes here are broadly equivalent. For example the vegan and vegetarian diets in Erb et al (2016) have a central value for cropland area of approximately 1200 and 1000 Mha, respectively, compared to the low meat diet used here (based on the average diet in India) of 1022 Mha. As expected, for the reasons given above, changes in intensity considered in Erb et al (2016) but not here appear to moderate the land use outcomes, i.e.…”

Section: P Alexander Et Almentioning

confidence: 99%

“…There has also been an increasing number of studies considering the impact of alternative assumptions regarding future diets, such as lower animal product consumption, healthy diets, vegetarianism or veganism, e.g. (Bajželj et al, 2014;Erb et al, 2016;Haberl et al, 2011;Mora et al, 2016;Popp et al, 2010;Stehfest et al, 2009). However, technology changes or radical alteration of consumer preferences, which could be transformative for the food system, remain unexplored.…”

Section: Introductionmentioning

confidence: 96%

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Could consumption of insects, cultured meat or imitation meat reduce global agricultural land use?

Alexander

Brown

Arneth

et al. 2017

Global Food Security

267

124

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A B S T R A C TAnimal products, i.e. meat, milk and eggs, provide an important component in global diets, but livestock dominate agricultural land use by area and are a major source of greenhouse gases. Cultural and personal associations with animal product consumption create barriers to moderating consumption, and hence reduced environmental impacts. Here we review alternatives to conventional animal products, including cultured meat, imitation meat and insects (i.e. entomophagy), and explore the potential change in global agricultural land requirements associated with each alternative. Stylised transformative consumption scenarios where half of current conventional animal products are substituted to provide at least equal protein and calories are considered. The analysis also considers and compares the agricultural land area given shifts between conventional animal product consumption. The results suggest that imitation meat and insects have the highest land use efficiency, but the land use requirements are only slightly greater for eggs and poultry meat. The efficiency of insects and their ability to convert agricultural by-products and food waste into food, suggests further research into insect production is warranted. Cultured meat does not appear to offer substantial benefits over poultry meat or eggs, with similar conversion efficiency, but higher direct energy requirements. Comparison with the land use savings from reduced consumer waste, including over-consumption, suggests greater benefits could be achieved from alternative dietary transformations considered. We conclude that although a diet with lower rates of animal product consumption is likely to create the greatest reduction in agricultural land, a mix of smaller changes in consumer behaviour, such as replacing beef with chicken, reducing food waste and potentially introducing insects more commonly into diets, would also achieve land savings and a more sustainable food system.

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Section: P Alexander Et Almentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

Could consumption of insects, cultured meat or imitation meat reduce global agricultural land use?

Alexander

Brown

Arneth

et al. 2017

Global Food Security

267

124

View full text Add to dashboard Cite

show abstract

“…In an AD model containing APP SWE and the N141I mutation in PS2, genes that were altered in whole brain tissue were found to be highly enriched in microglia and astrocytes; however, only a fraction of these genes was in fact up‐regulated when examined in these cell types as a specific population. Of these, microglia accounted for 87% (Kim et al, ). Single‐cell RNAseq continually reports multiple glial cell populations, even in wild‐type mice (Zeisel et al, ).…”

Section: Microglia Transcriptomic Changes In Admentioning

confidence: 99%

The involvement of microglia in Alzheimer's disease: a new dog in the fight

Moore

Crack

2018

British J Pharmacology

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First described clinically in 1906, Alzheimer's disease (AD) is the most common neurodegenerative disease and form of dementia worldwide. Despite its prevalence, only five therapies are currently approved for AD, all dealing with the symptoms rather than the underlying causes of the disease. A multitude of experimental evidence has suggested that the once thought inconsequential process of neuroinflammation does, in fact, contribute to the AD pathogenesis. One such CNS cell type critical to this process are microglia. Plastic in nature with varied roles, microglia are emerging as key contributors to AD pathology. This review will focus on the role of microglia in the neuroinflammatory response in AD, highlighting recent studies implicating aberrant changes in microglial function in disease progression. Of critical note is that with these advances, a reconceptualization of the framework in which we view microglia is required. Linked Articles This article is part of a themed section on Therapeutics for Dementia and Alzheimer's Disease: New Directions for Precision Medicine. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.18/issuetoc

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“…Combining a LOV domain adjacent to a localisation signal results in cytoplasmic localization, which upon light activation exposes the localization signal triggering re-localization (Yumerefendi et al, 2016). Several variants of this technique exist, such as LEXY, LINuS, LANS or LINX which consist of the concealment of nuclear export (NES) or/and nuclear localization (NLS) signals by LOV2, respectively (Niopek et al, 2014, 2016; Di Ventura and Kuhlman, 2016; Wehler et al, 2016; Yumerefendi et al, 2016). All of these modifications are short and genetically encoded domains that can be joined at the C - or N - terminus of proteins of interest (Wehler et al, 2016).…”

Section: The First-light On Optogeneticsmentioning

confidence: 99%

How to Train a Cell–Cutting-Edge Molecular Tools

et al. 2017

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In biological systems, the formation of molecular complexes is the currency for all cellular processes. Traditionally, functional experimentation was targeted to single molecular players in order to understand its effects in a cell or animal phenotype. In the last few years, we have been experiencing rapid progress in the development of ground-breaking molecular biology tools that affect the metabolic, structural, morphological, and (epi)genetic instructions of cells by chemical, optical (optogenetic) and mechanical inputs. Such precise dissection of cellular processes is not only essential for a better understanding of biological systems, but will also allow us to better diagnose and fix common dysfunctions. Here, we present several of these emerging and innovative techniques by providing the reader with elegant examples on how these tools have been implemented in cells, and, in some cases, organisms, to unravel molecular processes in minute detail. We also discuss their advantages and disadvantages with particular focus on their translation to multicellular organisms for in vivo spatiotemporal regulation. We envision that further developments of these tools will not only help solve the processes of life, but will give rise to novel clinical and industrial applications.

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Low-dielectric-constant polyimide aerogel composite films with low water uptake

Cited by 148 publications

References 31 publications

Could consumption of insects, cultured meat or imitation meat reduce global agricultural land use?

Could consumption of insects, cultured meat or imitation meat reduce global agricultural land use?

The involvement of microglia in Alzheimer's disease: a new dog in the fight

How to Train a Cell–Cutting-Edge Molecular Tools

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