“…The test zone of the electrochemical cell was then loaded with glucose oxidase, lactate oxidase, and uricase to detect glucose, lactate, and uric acid, respectively. After this pioneering work, several electrochemical paper-based sensors were developed using different paper-based substrates, such as Japanese paper [9], standard filter paper (e.g., Cordenons) [10], office paper [11], and chromatography paper (e.g., Whatman #1), [12,13]). However, these paper types are not suitable for printed electronics since the substrate should be characterized by minimized roughness and low humidity sensitivity.…”