Low Cost Lab on Chip for the Colorimetric Detection of Nitrate in Mineral Water Products

Khanfar, Mohammad F.; Al-Faqheri, Wisam; Al-Halhouli, Ala’aldeen

doi:10.3390/s17102345

Cited by 42 publications

(24 citation statements)

References 18 publications

(18 reference statements)

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“…The other factor is the solid phase extraction technique used in this study, which is responsible for the removal of most of the contaminants and interfering agents that may reduce the system ability to detect the nitrite. As a consequence, 6.3 times enhancement in the limit of detection is achieved with a LOD of 1.24 × 10 −2 ppm [17].…”

Section: Resultsmentioning

confidence: 99%

“…The detection of nitrite in samples of different origins such as natural waters, processed meats, and biological samples like urine and blood plasma has been carried out by different research groups [11,12,13,14,15,16,17]. The ion could be detected by the three key instrumental methods, namely ion chromatography, electrochemistry (both potentiometry and voltammetry), and spectrometry.…”

Section: Introductionmentioning

confidence: 99%

“…The detection of nitrite by miniaturized systems has been performed by different research groups across the world [14,16,17,25,26]. Key examples on the utilized systems are listed in Table 1.…”

Section: Introductionmentioning

confidence: 99%

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Lab on a Chip for the Colorimetric Determination of Nitrite in Processed Meat Products in the Jordanian Market

et al. 2019

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Nitrite and Nitrate have been used extensively as additives in various meat products to enhance flavor, color, and to preserve the meat from the bacterial growth. High concentrations of nitrite can threat human health since several studies in the literature claim that nitrite is associated with cancer incidences, leukemia, and brain tumors. Therefore, it is vital to measure the nitrite concentrations in processed meat products. In this study, an in-lab miniaturized photometric detection system is fabricated to inspect the nitrite concentration in processed meat products in Jordan. The analytical performance of nitrite detection is evaluated based on three key statistical parameters; linearity, limit of detection, and limit of quantitation. Respectively, for the fabricated system, the three values are found to be equal to 0.995, 1.24 × 10−2 ppm, and 4.12 × 10−2 ppm. Adherence to Beer’s law is found over the investigated range from 2.63 ppm to 96.0 ppm. The developed system is utilized for photometric detection of nitrite in processed meat products available in the Jordanian market like pastrami, salami, and corned beef. In all of the analyzed samples, the nitrite content is found to be lower than 150 ppm, which represents the maximum allowable nitrite limit.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Lab on a Chip for the Colorimetric Determination of Nitrite in Processed Meat Products in the Jordanian Market

et al. 2019

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“…Our experience shows clearly that every stage in a new project takes longer than expected. Publications showcasing the "do-it-yourself" approach often present the methodology and schematics for a functioning sensor, followed by a brief reflection on accuracy and future applications (e.g., Khanfar et al, 2017;Beddows andMallon, 2018, Metzger et al, 2018). These guides rarely comment on the time commitment.…”

Section: Timementioning

confidence: 99%

Low-cost electronic sensors for environmental research: pitfalls and opportunities

Chan¹,

Schillereff²,

Baas³

et al. 2019

Preprint

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Repeat observations underpin our understanding of environmental processes but financial constraints often limit scientists’ ability to deploy dense networks of conventional commercial instrumentation. Rapid growth in the Internet-Of-Things (IOT) and the maker movement is paving the way for low-cost electronic sensors to transform global environmental monitoring. Accessible and inexpensive sensor construction is also fostering exciting opportunities for citizen science and participatory research. Drawing on six years of developmental work with Arduino open-source hardware and software and active field research, we outline a series of successes, failures and lessons learned in designing and deploying environmental sensors. Six case studies are presented: a water table depth probe, air and water quality sensors, multi-parameter weather stations, a time-sequencing lake sediment trap and a sonic anemometer for monitoring sand transport. Sensor design and schematics are described alongside an evaluation of pitfalls and future improvements for individual sensors and the workflow process. We show that manual design and construction can produce research-grade scientific instruments for a fraction of the conventional cost. In sharing our collective experiences with build-it-yourself environmental monitoring, we intend for this paper to act as a platform for scientists and educators to delve into low-cost sensor development. This will ultimately lead to superior environmental monitoring at higher spatial and temporal resolution from the local to global scales.

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“…For the last few decades, the ability to miniaturize complex processes using lab-on-a-chip (LOC) technology has drawn great attention from researchers in the chemical, pharmaceutical, and biological fields [1][2][3][4]. Compared to traditional analysis tools, LOC can achieve highly sensitive and reliable results with improved processing time, reduced sample volume, higher flexibility, and portability [5]. With such integration, flexibility, and automation, LOC can perform multi-stepped assays without the need for a skilled operator, minimal or no laboratory tools, and simple operational protocols that make results more reliable with minimum human error.…”

Section: Introductionmentioning

confidence: 99%

Development of Active Centrifugal Pump for Microfluidic CD Platforms

et al. 2020

Self Cite

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The continuous emerging of microfluidic compact disc (CD) platforms for various real-life applications motivates researchers to explore new innovative ideas towards more integrated active functions. However, microfluidic CDs have some drawbacks, including the unidirectional flow that limits the usable space for multi-stepped biological and chemical assays. In this work, a novel active and bidirectional centrifugal pump is developed and integrated on microfluidic CDs. The design of the developed pump partially replicates the designs of the conventional centrifugal pumps with a modification in the connecting channels’ positions that allow the developed pump to be reversible. The main advantage of the proposed centrifugal pump is that the pumping speed can be accurately controlled during spinning or while the microfluidic CD is stationary. Performance tests show that the pumping speed can reach up to 164.93 mm3/s at a pump rotational speed (impellers speed) of 4288 rpm. At that speed, 1 mL of water could be pumped in 6.06 s. To present a few of the potential applications of the centrifugal pump, flow reciprocation, bidirectional pumping, and flow switching were performed and evaluated. Results show that the developed centrifugal pump can pump 1096 µL of liquid towards the CD center at 87% pumping efficiency while spinning the microfluidic CD at 250 rpm. This novel centrifugal pump can significantly widen the range of the applicability of microfluidic CDs in advanced chemical processes and biological assays.

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Low Cost Lab on Chip for the Colorimetric Detection of Nitrate in Mineral Water Products

Cited by 42 publications

References 18 publications

Lab on a Chip for the Colorimetric Determination of Nitrite in Processed Meat Products in the Jordanian Market

Lab on a Chip for the Colorimetric Determination of Nitrite in Processed Meat Products in the Jordanian Market

Low-cost electronic sensors for environmental research: pitfalls and opportunities

Development of Active Centrifugal Pump for Microfluidic CD Platforms

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