Long-Term Results of Substrate-Based Ventricular Tachycardia Ablation in Patients With Previous Myocardial Infarction. Identification of Anatomical and Electrophysiological Success Predictors

Arenal, Ángel; Eidelman, Gabriel; Calvo, David; Atienza, Felipe; Atéa, Leonardo; Datino, Tomás; Torrecilla, Esteban G.; Miracle, Ángel; J, Hernández; Ceballos, Cecilia; Fernández-Avilés, Francisco

doi:10.1016/s0735-1097(11)60071-5

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“…Indications for catheter ablation in VT are clearly defined (2), and there is extensive literature available on factors that influence VT ablation success (8). However, female patients are underrepresented in the existing studies, therefore sex differences among predictors of VT recurrence or mortality following VT ablation are not known.…”

Section: Introductionmentioning

confidence: 99%

Sex differences in one-year recurrence and all-cause mortality following catheter ablation of ventricular tachycardia in structural heart disease

Komlósi²,

Vámosi³

et al. 2022

Front. Cardiovasc. Med.

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AimsWe aimed to establish sex-specific predictors for 1-year VT recurrence and 1-year all-cause mortality in patients with structural heart disease undergoing catheter ablation.MethodsWe analyzed data of 299 patients recorded in our structured registry. These included medical history, echocardiography parameters, laboratory results, VT properties, procedural data.ResultsOut of the 299 patients, 34 (11%) were female. No significant difference was found between women and men in terms of VT recurrence (p = 0.74) or mortality (p = 0.07). In females, severe mitral regurgitation (MR), tricuspid regurgitation (TR), presentation with incessant VT, and preprocedural electrical storm (ES) were associated with increased risk of VT recurrence. Diabetes, implanted CRT, VT with hemodynamic instability, ES and advanced MR were the risk factors of mortality in women. ACEi/ARB use predicted a favorable outcome in both endpoints among females. In men, independent predictors of VT recurrence were the composite parameter of ES and multiple ICD therapies, presentation with incessant VT, severe MR, while independent predictors of mortality were age, LVEF, creatinine and previously implanted CRT.ConclusionAccording to our investigation, there are pronounced sex differences in predictors of recurrence and mortality following VT ablation.

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Section: Introductionmentioning

confidence: 99%