Long-term follow-up of bilateral botulinum toxin injections versus bilateral recessions of the medial rectus muscles for treatment of infantile esotropia

Gürsoy, Hüseyin; Başmak, Hikmet; Şahin, Afsun; Yıldırım, Nilgün; Aydın, Yasemin; Çolak, Ertuğrul

doi:10.1016/j.jaapos.2012.01.010

Cited by 45 publications

(40 citation statements)

References 20 publications

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“…8,12,15,16 Others opted for no EMG assistance. 11,13,17,18 Campos et al 14 performed the injections under direct visualization of the muscle. …”

Section: Discussionmentioning

confidence: 99%

“…Lastly, Gursoy et al 18 performed a prospective report. They compared the results of BT injection versus muscle surgery to treat infantile esotropia.…”

Section: Description Of Studiesmentioning

confidence: 99%

“…8,[13][14][15][16][17][18] Also, many studies show that multiple injections may be needed to sustain the alignment effect. 19 On the other hand, the advantage is that BT is a simple treatment, in which injections are performed under minimal anesthesia without intubation.…”

mentioning

confidence: 99%

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The Use of Botulinum Toxin to Treat Infantile Esotropia: A Systematic Review With Meta-Analysis

Issaho

Carvalho

Tabuse

et al. 2017

Invest. Ophthalmol. Vis. Sci.

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Citation: Issaho DC, Carvalho FRS, Tabuse MKU, Carrijo-Carvalho LC, de Freitas D. The use of botulinum toxin to treat infantile esotropia: a systematic review with meta-analysis. Invest Ophthalmol Vis Sci. 2017;58:5468-5476. DOI:10.1167/iovs.17-22576 PURPOSE. The purpose of this review was to examine the efficacy of botulinum toxin in the treatment of infantile esotropia and to evaluate the average response of BT and its complication rates. METHODS. A research was performed in the Latin American and Caribbean Literature on Health Sciences (LILACS), MEDLINE, and Cochrane Central Register of Controlled Trial (CENTRAL).The database was searched between December 28, 2016 and January 30, 2017. The selection was restricted to articles published in English, Spanish, or Portuguese. There were no date restrictions in the search.RESULTS. Nine studies were eligible for inclusion. The grouped success rate of BT treatment in infantile esotropia was 76% (95% confidence interval [CI]: 61%-89%). For the success rate, I 2 of 94.25% was observed, indicating a high heterogeneity (P < 0.001). The complication rates were also analyzed. The grouped consecutive exotropia (XT) rate was 1% (95% CI: 0%-2%). The grouped ptosis rate was 27% (95% CI: 21%-33%). The grouped vertical deviation rate was 12% (95% CI: 4%-22%). The mean change of the deviation after BT injection was À30.7 (95% CI: À37.7, À23.8), demonstrating a significant improvement in alignment.CONCLUSIONS. Botulinum toxin injection into medial recti muscles reveals to be a safe procedure and a valuable alternative to strabismus surgery in congenital esotropia, especially in moderate deviations.

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“…8,12,15,16 Others opted for no EMG assistance. 11,13,17,18 Campos et al 14 performed the injections under direct visualization of the muscle. …”

Section: Discussionmentioning

confidence: 99%

“…Lastly, Gursoy et al 18 performed a prospective report. They compared the results of BT injection versus muscle surgery to treat infantile esotropia.…”

Section: Description Of Studiesmentioning

confidence: 99%

See 1 more Smart Citation

The Use of Botulinum Toxin to Treat Infantile Esotropia: A Systematic Review With Meta-Analysis

Issaho

Carvalho

Tabuse

et al. 2017

Invest. Ophthalmol. Vis. Sci.

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“…In studies with infantile or acquired esotropic patients, no difference has been reported between the outcomes of BTX A and surgery. However, BTX A has appeared to be less effective than surgery for patients with horizontal deviation and poor binocular vision (9,10) .…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Botulinum Toxin A Injection in Horizontal Strabismus

Yıldırım¹,

Tetikoğlu²,

Kuru³

et al. 2017

Okmeydani Medical Journal

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Objective: To evaulate the efficacy of botulinum toxin A injection and factors affecting the treatment in strabismus. Material and Methods: Botulinum toxin A administered 43 patients with the diagnosis of horizontal deviation in 26'sında (%60,5) ezotropya mevcutken, 17'sinde (%39,5) ekzotropta vardı. Hastaların 16'sı (%37,2) rezidüel şaşılık, 19'u (%44,2) paralitik şaşılık, 8'i (%18,6) ise konsekütiv şaşılık idi. Otuz (%69,[8][9][10][11][12][13][14][15][16][17][18][19][20] 13 (%30,2)

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“…Horizontal şaşılıklarda sütürlerin skleradan geçirile-rek uygulandığı konvansiyonel geriletme cerrahileri yüz yılı aşkın süredir uygulanmaktadır (3,4) . Ancak, skleradan sütürlerin geçirilmesinin getirdiği bazı sıkıntılar, özellikle seçilmiş olgularda cerrahi tekniklerin değiştirlmesini veya botoks enjeksiyonunu gün-deme getirmiştir (3)(4)(5) . Horizontal rektus kasının skleraya direkt sütüre edilmesi sonrası klinik önemi her olguda bilinmemekle beraber %0,4 ile %2,8 arası oranlarda retinada mikroperforasyonlar bildirilmiştir (6) .…”

Section: Introductionunclassified

The Comparison of the Strabismus Cases Who Underwent Conventional Recession Surgery with the Cases Who Underwent Hang-Back Recession

Gürsoy¹,

Bilgeç²,

Kucukiba³

et al. 2016

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Long-term follow-up of bilateral botulinum toxin injections versus bilateral recessions of the medial rectus muscles for treatment of infantile esotropia

Cited by 45 publications

References 20 publications

The Use of Botulinum Toxin to Treat Infantile Esotropia: A Systematic Review With Meta-Analysis

The Use of Botulinum Toxin to Treat Infantile Esotropia: A Systematic Review With Meta-Analysis

Efficacy of Botulinum Toxin A Injection in Horizontal Strabismus

The Comparison of the Strabismus Cases Who Underwent Conventional Recession Surgery with the Cases Who Underwent Hang-Back Recession

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