1985
DOI: 10.1111/j.1471-0528.1985.tb01091.x
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Long‐term effects of the menopause and sex hormones on skin thickness

Abstract: Suniiriary. Skin collagcn conlcnt a~~d skin thickness in a g r o u p of postinenopausal wonicn w h o had been treated with sex h o r m o n c implants were c o m p a r e d with those in a n untreated g r o u p of similar w o m e n . Both skin collagen content and thickness were found t o b e significantly greater in the treated than in the untreated group. In the untreated women skin collagen content declined in re1 a 1' ion to m e n opausal age but not t o chronological age. No correlation was found with menop… Show more

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Cited by 240 publications
(94 citation statements)
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“…For women particularly in the post-menopausal years, acceleration of chronologic aging is enhanced by the loss of estrogen, which causes a rapid loss of collagen during the first 5 years after menopause (Brincat et al, 1983;Brincat et al, 1985;Brincat et al, 1987;Brincat, 2000). It is assumed that phytoestrogens such as soy isoflavones may mimic the effects of estrogen in skin and reduce skin changes in postmenopausal women.…”
Section: Discussionmentioning
confidence: 99%
“…For women particularly in the post-menopausal years, acceleration of chronologic aging is enhanced by the loss of estrogen, which causes a rapid loss of collagen during the first 5 years after menopause (Brincat et al, 1983;Brincat et al, 1985;Brincat et al, 1987;Brincat, 2000). It is assumed that phytoestrogens such as soy isoflavones may mimic the effects of estrogen in skin and reduce skin changes in postmenopausal women.…”
Section: Discussionmentioning
confidence: 99%
“…Among these factors, the severity of wrinkles correlates strongly with age. As human skin ages, it becomes thin and shows a decrease in elasticity, glycosamino glycans, and collagen [18,[20][21][22][23].…”
Section: Introductionmentioning
confidence: 99%
“…In humans, due to aging the skin becomes thin, decrease elasticity and the content of glycosamino glycans, collagen, etc. [50,51]. The data suggests that the both Biofield Energy Treated test formulation and DMEM could be significantly used for antiwrinkling activity.…”
Section: Anti-wrinkle Effect Of the Test Formulation On Hff-1 Cells Amentioning
confidence: 82%