(-)-Loliolide, the most ubiquitous lactone, is involved in barnyardgrass-induced rice allelopathy

Kong

Plant Cell & Environment

et al. 2020

Self Cite

133

100

Plant-to-plant signalling is a key mediator of interactions among plant species. Plants can perceive and respond to chemical cues emitted from their neighbours, altering survival and performance, impacting plant coexistence and community assembly. An increasing number of studies indicate root exudates as key players in plant-to-plant signalling. Root exudates mediate root detection and behaviour, kin recognition, flowering and production, driving inter-and intra-specific facilitation in cropping systems and mixed-species plantations. Altered interactions may be attributed to the signalling components within root exudates. Root ethylene, strigolactones, jasmonic acid, (-)-loliolide and allantoin are signalling chemicals that convey information on local conditions in plant-plant interactions. These root-secreted signalling chemicals appear ubiquitous in plants and trigger a series of belowground responses inter-and intra-specifically, involving molecular events in biosynthesis, secretion and action. The secretion of root signals, mainly mediated by ATP-binding cassette transporters, is critical. Root-secreted signalling chemicals and their molecular mechanisms are rapidly revealing a multitude of fascinating plant-plant interactions. However, many root signals, particularly species-specific signals and their underlying mechanisms, remain to be uncovered due to methodological limitations and root-soil interactions. A thorough understanding of root-secreted chemical signals and their mechanisms will offer many ecological implications and potential applications for sustainable agriculture.

Section: Signalling Chemicals and Their Methodological Approachesmentioning

confidence: 99%

Root exudate signals in plant–plant interactions

Kong

Plant Cell & Environment

et al. 2020

Self Cite

133

100

“…The sessile lifestyle of plants necessitates a great arsenal of metabolites that protect against herbivores and pathogens. This arsenal includes the so‐called plant activators, such as the phytohormone jasmonic acid (JA), which is involved in plant–pathogen protection through the activation of defense mechanisms that do not harm/kill the microbes or insects (Wei et al ., 2011; Caceres et al ., 2016; Murata et al ., 2019a,b; Li et al ., 2020). In addition, plants defend themselves by using metabolites that affect pathogens and exert antimicrobial or insecticidal activity.…”

Section: Cyclic and Acyclic Apocarotenoids With Signaling Propertiesmentioning

confidence: 99%

“…In addition, plants defend themselves by using metabolites that affect pathogens and exert antimicrobial or insecticidal activity. Interestingly, several cyclic apocarotenoids that induce herbivore resistance in plants without exhibiting insecticidal activity have been reported in the last years (Wei et al ., 2011; Caceres et al ., 2016; Murata et al ., 2019a,b; Li et al ., 2020). Examples of such apocarotenoids are α‐ionone, β‐ionone and loliolide, which arise through the degradation of α‐ and β‐carotene (Schwab et al ., 2008).…”

Section: Cyclic and Acyclic Apocarotenoids With Signaling Propertiesmentioning

confidence: 99%

“…(–)‐Loliolide was also recently reported as a soil‐borne signaling chemical conserved in dozens of plants (Kong et al ., 2018). For instance, (–)‐loliolide was detected in the barnyard grass–rice allelopathic interaction (Li et al ., 2020). The interaction between rice and five biotypes of barnyard grass was characterized by the higher levels of the allelochemicals momilactone B (a diterpenoid) and tricin (a flavonoid), measured in rice, in response to (–)‐loliolide, which was detected in the root exudates of all five biotypes of barnyard grass.…”

Section: Cyclic and Acyclic Apocarotenoids With Signaling Propertiesmentioning

confidence: 99%

See 1 more Smart Citation

Plant apocarotenoids: from retrograde signaling to interspecific communication

et al. 2021

Summary Carotenoids are isoprenoid compounds synthesized by all photosynthetic and some non‐photosynthetic organisms. They are essential for photosynthesis and contribute to many other aspects of a plant's life. The oxidative breakdown of carotenoids gives rise to the formation of a diverse family of essential metabolites called apocarotenoids. This metabolic process either takes place spontaneously through reactive oxygen species or is catalyzed by enzymes generally belonging to the CAROTENOID CLEAVAGE DIOXYGENASE family. Apocarotenoids include the phytohormones abscisic acid and strigolactones (SLs), signaling molecules and growth regulators. Abscisic acid and SLs are vital in regulating plant growth, development and stress response. SLs are also an essential component in plants’ rhizospheric communication with symbionts and parasites. Other apocarotenoid small molecules, such as blumenols, mycorradicins, zaxinone, anchorene, β‐cyclocitral, β‐cyclogeranic acid, β‐ionone and loliolide, are involved in plant growth and development, and/or contribute to different processes, including arbuscular mycorrhiza symbiosis, abiotic stress response, plant–plant and plant–herbivore interactions and plastid retrograde signaling. There are also indications for the presence of structurally unidentified linear cis‐carotene‐derived apocarotenoids, which are presumed to modulate plastid biogenesis and leaf morphology, among other developmental processes. Here, we provide an overview on the biology of old, recently discovered and supposed plant apocarotenoid signaling molecules, describing their biosynthesis, developmental and physiological functions, and role as a messenger in plant communication.

“…It was also found in marine ecosystems in different brown seaweeds, such as Sargassum horneri [35],Sargassum ringgoldianum subsp. coreanum [36], and Undaria pinnatifida [37], revealing antioxidant, anti-fungal, antibacterial and anticancer properties [34][35][36].…”

Section: Introductionmentioning

confidence: 99%

Loliolide, a New Therapeutic Option for Neurological Diseases? In Vitro Neuroprotective and Anti-Inflammatory Activities of a Monoterpenoid Lactone Isolated from Codium tomentosum

Silva

Alves

Martins

et al. 2021

IJMS

Parkinsons Disease (PD) is the second most common neurodegenerative disease worldwide, and is characterized by a progressive degeneration of dopaminergic neurons. Without an effective treatment, it is crucial to find new therapeutic options to fight the neurodegenerative process, which may arise from marine resources. Accordingly, the goal of the present work was to evaluate the ability of the monoterpenoid lactone Loliolide, isolated from the green seaweed Codium tomentosum, to prevent neurological cell death mediated by the neurotoxin 6-hydroxydopamine (6-OHDA) on SH-SY5Y cells and their anti-inflammatory effects in RAW 264.7 macrophages. Loliolide was obtained from the diethyl ether extract, purified through column chromatography and identified by NMR spectroscopy. The neuroprotective effects were evaluated by the MTT method. Cells´ exposure to 6-OHDA in the presence of Loliolide led to an increase of cells´ viability in 40%, and this effect was mediated by mitochondrial protection, reduction of oxidative stress condition and apoptosis, and inhibition of the NF-kB pathway. Additionally, Loliolide also suppressed nitric oxide production and inhibited the production of TNF-α and IL-6 pro-inflammatory cytokines. The results suggest that Loliolide can inspire the development of new neuroprotective therapeutic agents and thus, more detailed studies should be considered to validate its pharmacological potential.