Localized lymphadenitis due to leishmania. Diagnosis by fine needle aspiration cytology

García‐González, Ricardo; Sanz, I; Saus, Carlos; Calleja, José Luís

doi:10.1136/pgmj.66.774.326

Cited by 8 publications

(11 citation statements)

References 2 publications

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“…We diagnosed a substantial number of cases of LLL, an atypical presentation that has rarely been reported in the literature [5][6][7][8][9]. To our knowledge, this is the first series of cases of LLL caused by L. infantum, and we compared it to VL during the outbreak.…”

Section: Discussionmentioning

confidence: 91%

“…Nevertheless, in the Mediterranean area, isolated cases of an infrequent form of leishmaniasis involving isolated lymphadenopathies without fever or skin lesions have been described in a few case reports as localized leishmanial lymphadenopathy (LLL) [5][6][7][8][9]. The clinical management of LLL is not well defined because it is not a classic form of VL or CL [5,8].…”

Section: Introductionmentioning

confidence: 99%

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Atypical presentation in adults in the largest community outbreak of leishmaniasis in Europe (Fuenlabrada, Spain)

Horrillo¹,

Martín

Molina

et al. 2015

Clinical Microbiology and Infection

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Since 2009, the largest reported outbreak of leishmaniasis by Leishmania infantum in Europe was reported in Fuenlabrada, Spain. In our hospital, 90 adults with localized leishmanial lymphadenopathy (LLL) or visceral leishmaniasis (VL) were treated during this outbreak; 72% were men, and the mean age was 46.2 years (range 15-95 years). A total of 17 cases (19%) were LLL, an atypical form with isolated lymphadenopathies without other symptoms. All LLL cases occurred in immunocompetent subjects, and only one subject (6%) was a native of sub-Saharan Africa. Diagnosis was performed by fine needle aspiration cytology of the lymphadenopathy. Serology was negative in 38%. LLL outcomes at 6 months were benign, even with doses of liposomal amphotericin B that were often lower (10 mg/kg) than those recommended for VL in Mediterranean areas. A total of 73 subjects (81%) presented with typical VL; 66% of this group were immunocompetent, and 50% of those who were immunocompetent were descendants of natives of sub-Saharan Africa. The rK39 test and polymerase chain reaction were the most useful tests for confirmation of the diagnosis. An initial response to treatment was observed in 99% of cases, and relapses occurred in 14% of cases. Leishmaniasis should be included in the differential diagnosis of isolated lymphadenopathies in endemic areas. LLL could be considered a more benign entity, one different than VL, and less aggressive management should be studied in future investigations.

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Section: Discussionmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Atypical presentation in adults in the largest community outbreak of leishmaniasis in Europe (Fuenlabrada, Spain)

Horrillo¹,

Martín

Molina

et al. 2015

Clinical Microbiology and Infection

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show abstract

“…The FNA diagnosis of localized Leishmania lymphadenitis has been described rarely. [6][7][8]10,12,13 We describe our experience with 133 cases of localized Leishmania lymphadenitis that were diagnosed from FNA smears during a period of 15 years.…”

Section: Objective: To Describe the Cytologic Findings Of Localizedmentioning

confidence: 99%

Subclassification of Localized <i>Leishmania</i> Lymphadenitis in Fine Needle Aspiration Smears

Kumar

Moosavi²,

Karimi³

et al. 2001

Acta Cytologica

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“…7 A rapid diagnosis of this condition can greatly expedite the initiation of therapy. Although a look at the available literature suggests that fine needle aspiration cytology (FNAC) is a reliable mode of diagnosis in cases of Leishmania lymphadenitis, 3,5,9,10 there are only very few reports 1,4 describing its usefulness in the diagnosis of cutaneous leishmaniasis, whereas the use of scrape smears and skin biopsy appears to be much more popular. Below we present a case of cutaneous leishmaniasis in a 6-month-old child in whom FNAC smears showed the amastigote form of Leishmania; that led to a rapid diagnosis.…”

Section: Background: Skin Biopsy and Scrape Smear Examination Are Thementioning

confidence: 99%

Fine Needle Aspiration Cytology Diagnosis of Cutaneous Leishmaniasis in a 6-Month-Old Child

Mallik¹,

Das²,

Haji³

2001

Acta Cytologica

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Localized lymphadenitis due to leishmania. Diagnosis by fine needle aspiration cytology

Cited by 8 publications

References 2 publications

Atypical presentation in adults in the largest community outbreak of leishmaniasis in Europe (Fuenlabrada, Spain)

Atypical presentation in adults in the largest community outbreak of leishmaniasis in Europe (Fuenlabrada, Spain)

Subclassification of Localized <i>Leishmania</i> Lymphadenitis in Fine Needle Aspiration Smears

Fine Needle Aspiration Cytology Diagnosis of Cutaneous Leishmaniasis in a 6-Month-Old Child

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