Subclassification of Localized <i>Leishmania</i> Lymphadenitis in Fine Needle Aspiration Smears

Fine Needle Aspiration of Lymphadenopathy in Visceral Leishmaniasis

“…In addition, LD bodies were easily demonstrated on FNA smears in the 2 groups of cases in our study, but LD bodies were identified only after an extensive search in the cases with group 3 morphology in the study done by Kumar et al 14 This, once again, may be due to differences in the pathogenesis of lymphadenopathy in VL, PKDL and localized Leishmania lymphadenitis.…”

“…Recently, Kumar et al, 14 from Iran, reported 133 cases of localized Leishmania lymphadenitis diagnosed on FNA. The cytologic findings in those cases were divided into 5 major groups: (1) acute inflammation with giant cells, (2) histiocytic granulomas, (3) epithelioid cell granulomas, (4) plasma cell type, and (5) mixed histioplasmacytic type.…”

New Cytologic Clues in Localized Leishmania Lymphadenitis

“…Cytologic findings of tuberculous lymphadenopathy such as granulomatous or suppurative inflammation is also seen in LLL, but caseation is never seen in leishmaniasis. [22][23][24][25] Giant cells observed in our cases were mostly of the foreign body type, and the Langhans type described by Kumar et al 7 was not present in our case series. Intrahistiocytic ghosts of organism resembling foamy histiocytes are also reported in tuberculous lymphadenitis and are positive by AFS; however, in LL they are degenerated organism and are AFS negative.…”

Localized Leishmanial Lymphadenopathy: An Unusual Manifestation of Leishmaniasis in a Traveler in Southern Europe

“…In Northeast Brazil, for example, cutaneous leishmaniasis due to L. (Viannia) braziliensis is constantly accompanied by an extensive lymphadenopathy (Harms et al 2005). Localized lymphadenopathy without any cutaneous or systemic manifestation is, however, a rare manifestation of leishmaniasis (Vera-Alvarez et al 1999, Harms et al 2001, Kumar et al 2001, Daneshbod et al 2007, Cardot-Leccia et al 2009). The enlarged lymph node is usually indolent and most frequently located in the neck region (supraclavivular, cervical, or nuchal), but other localizations, mainly postauricular, submental, axillary, and inguinal, have been also observed (Vera-Alvarez et al 1999, Kumar et al 2001, Daneshbod et al 2007, Cardot-Leccia et al 2009).…”