New Cytologic Clues in Localized Leishmania Lymphadenitis

Bone Marrow Aspiration Findings in Kala-Azar

“…By electron microscope, a Leishman body shows a double-layer, tubular membrane encasing the organism, an oval nucleus with peripheral chromatin, a rod-shaped kinetoplast and a target-shaped basal body, and sometimes a segment of flagellum is visible. 1,9,10 The complete form of LDB can be seen in aspiration of bone marrow, lymph node In this study 204 cases of bone marrow aspiration and 887 slides of documented cases of kala-azar were reviewed in order to find cytologic clues other than typical intrahistiocytic cytoplasmic and free LDBs.…”

“…10 True ReedSternberg cells are large cells with abundant cytoplasm and 2 or more nuclei with 2 or more inclusionlike nucleoli that express CD30 and CD15. 10 Although multinucleated giant cells are seen in granulomatous reaction, multinucleated giant cells were rare (16 cases) in bone marrow aspirates of VL.…”

Flowers in a bone marrow aspiration

“…Surprisingly, amastigotes were mostly in aggregates, forming different shapes resembling as follows: tear drop (Image 1A), clover leaf (Image 1B), ball (Image 1C), sunflowers (Image 1D,E), rossetes (Image 1F), ring and doughnut (Image 1G-I). Such aggregation has not been reported in lymph node aspiration or skin smears [1,2]. The patient received glucantim injections, which subsided the fever within the first week and splenomegaly regressed in the second week.…”

Fine Needle Aspiration of Salivary Gland Lesions with Multinucleated Giant Cells

“…Another was diagnosed as leishmaniasis after detecting typical Leishman bodies ( Figure 5) (case 11). 10 There was a parotid FNA smear with many isolated and aggregate histiocytes and scattered MNGCs; the histiocytes had bean-shaped nuclei with longitudinal grooves (Figure 6A and B). A preliminary diagnosis of eosinophilic granuloma was made and confirmed on excisional biopsy ( Figure 6C …”