Localized delivery of active targeting micelles from nanofibers patch for effective breast cancer therapy

Mehnath, Sivaraj; Karuppannan, Chitra; Karthikeyan, K.; Jeyaraj, Murugaraj

doi:10.1016/j.ijpharm.2020.119412

Cited by 48 publications

(15 citation statements)

References 73 publications

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“…PCPP-CA-PHM nanofibers happened to show a restricted release of the sedate for a prolonged period compared to other nanofibers. Similarly, triaxial acid nanofibers, PVA-chitosan-polylactide, showed regulated release of the drug too [75] .…”

Section: Electrospun Nanofibrous Drug Delivery System For Chemotherapymentioning

confidence: 99%

A review on allopathic and herbal nanofibrous drug delivery vehicles for cancer treatments

Mateti

Aswath

Vatti

et al. 2021

Biotechnology Reports

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Highlights The life-threatening side effects of cancer treatment are addressed using nano-formulations and combinational therapy. Herbal drugs displayed potency in curing cancer using a nanofiber based device. Allopathic anti-cancer drugs can be delivered at a targeted site using a nanofiber based drug carrier which improves bioavailability to a great extent. A combination of an herbal and allopathic anticancer drug could be a possible life-saving union to cure cancer.

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Section: Electrospun Nanofibrous Drug Delivery System For Chemotherapymentioning

confidence: 99%

A review on allopathic and herbal nanofibrous drug delivery vehicles for cancer treatments

Mateti

Aswath

Vatti

et al. 2021

Biotechnology Reports

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“…An important role is played by the retention of the drug when it diffuses into the cells, by using the high permeability of the skin. With an adequate drug, the novel material could ensure a good response in therapeutic treatment in stimuli-responsive controlled delivery drug applications for breast cancer therapy [ 70 ].…”

Section: Resultsmentioning

confidence: 99%

Preparation and Characterization of Electrospun Collagen Based Composites for Biomedical Applications

Drobotă¹,

Grădinaru²,

Vlad³

et al. 2020

Materials

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Electrospinning is a widely used technology for obtaining nanofibers from synthetic and natural polymers. In this study, electrospun mats from collagen (C), polyethylene terephthalate (PET) and a blend of the two (C-PET) were prepared and stabilized through a cross-linking process. The aim of this research was to prepare and characterize the nanofiber structure by Fourier-transform infrared with attenuated total reflectance spectroscopy (FTIR-ATR) in close correlation with dynamic vapor sorption (DVS). The studies indicated that C-PET nanofibrous mats shows improved mechanical properties compared to collagen samples. A correlation between morphological, structural and cytotoxic proprieties of the studied samples were emphasized and the results suggest that the prepared nanofiber mats could be a promising candidate for tissue-engineering applications, especially dermal applications.

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“…This pH-responsive nature of the nanomaterial is highly suitable for drug delivery in an acidic cancer cell environment. 42,43 FTIR evaluated the detailed side-chain modulation of TPGS-HA-CA hydrogel nanoconjugates during swelling, represent in Figure 4D. Nanoconjugates swelling ability based on the pH, which represents in FTIR studies.…”

Section: Swelling Studiesmentioning

confidence: 99%

Engineered Hyaluronic Acid-Based Smart Nanoconjugates for Enhanced Intracellular Drug Delivery

Arjama¹,

Mehnath²,

Rajan³

et al. 2023

Journal of Pharmaceutical Sciences

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Localized delivery of active targeting micelles from nanofibers patch for effective breast cancer therapy

Cited by 48 publications

References 73 publications

A review on allopathic and herbal nanofibrous drug delivery vehicles for cancer treatments

A review on allopathic and herbal nanofibrous drug delivery vehicles for cancer treatments

Preparation and Characterization of Electrospun Collagen Based Composites for Biomedical Applications

Engineered Hyaluronic Acid-Based Smart Nanoconjugates for Enhanced Intracellular Drug Delivery

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