Localized argyria in an antique restorer

Localized cutaneous argyria

“…However, heavy metals including silver may be inadvertently introduced into the skin through occupational exposures, acupuncture, earrings, topical silver medications, and trauma, among other causes. 2,3 Argyria leads to a focal, gray discoloration that clinically resembles a melanocytic proliferation. [2][3][4] As seen here, the collagen fibers may be prominently coated with silver granules, leading to a pseudoochronosis appearance.…”

“…2,3 Argyria leads to a focal, gray discoloration that clinically resembles a melanocytic proliferation. [2][3][4] As seen here, the collagen fibers may be prominently coated with silver granules, leading to a pseudoochronosis appearance. 2 In this case, scanning electron microscopy with energy-dispersive spectroscopy helped to identify the elements within the patient's skin and explain the pigmented lesion.…”

A pigmented lesion on the earlobe

“…Localized argyria from topical treatments and dressings containing silver nitrate has been described. Occupational argyria may still be seen in workers in contact with silver electroplating solutions or photographic processing, as well as those handling silver, such as jewellers and antique restorers, but this tends to result in localized argyria.…”

Severe generalized argyria secondary to ingestion of colloidal silver protein

“…It was seen more commonly in the 19th Century associated with occupational exposure in silversmiths, miners and photographers 1 . Localized argyria is now occasionally seen in jewellery makers, silver electroplating technicians 2 and those undergoing acupuncture with silver needles. Systemic consumption may cause generalized argyria in those taking silver either as a coating for sweets 3 or as an alternative medicine 4 .…”