Lipomatous infiltration of the canine salivary gland

Abstract

Benign connective tumours of the canine salivary glands are rare. This report describes lipomatous infiltration of parotid or submandibular salivary glands in seven dogs in which the glands were enlarged as a result of infiltration by fat cells; they appeared to have been successfully treated by local excision. The precise cause of the lipomatous infiltration in the dogs is unclear but different causes of similar lesions in humans are discussed.

MR Anatomy of Salivary Glands in the Dog

“…Although MRI is becoming increasingly more essential in modern veterinary diagnostic investigations, literature review revealed just a single application in an experimental study for evaluating the function of a pilocarpine‐stimulated mandibular gland (Tsuchimochi et al., 1991). When considering sectional imaging techniques, only computed tomography was used to diagnose salivary gland neoplasia (Carberry et al., 1987; Brown et al., 1997; Sozmen et al., 2003; Shimoyama et al., 2006; Smrkovski et al., 2006; Faustino and Dias Pereira, 2007) and sialoceles or silaoliths (Hunt et al., 1997; Smrkovski et al., 2006; Bartoe et al., 2007; Trumpatori et al., 2007; McGill et al., 2009), even though MRI has superior soft‐tissue contrast (Klumpp et al., 2009).…”

Temporal Evolution of Parotid Volume and Parotid Apparent Diffusion Coefficient in Nasopharyngeal Carcinoma Patients Treated by Intensity-Modulated Radiotherapy Investigated by Magnetic Resonance Imaging: A Pilot Study

“…Although radiation-induced volume changes [ 18 – 24 ] and diffusional alternations [ 28 – 33 ] of parotid glands have been recently examined separately, mechanism of injury and recovery of parotid glands following parotid sparing radiotherapy still cannot be completely explained by either morphological change or physiological change alone. For example, reduced volume of parotid glands might be due to acinar loss [ 12 , 13 ] or fibrosis [ 13 ], while increased volume might be due to acute inflammation [ 36 ] or lipomatosis [ 37 , 38 ]. Besides, increased ADC might be due to acute inflammation or increased extravascular extracellular space due to cellular loss, while decreased ADC might be due to recovery from acute inflammation, increased cellularity [ 39 ] or abundant fatty component [ 40 ].…”

Lipomatosis of the canine parotid gland: case report with a literature review

“…Lipomatosis in canine salivary glands with unknown pathophysiology has been reported in 11 cases diagnosed postoperatively, including three cases without detailed descriptions 2 , 7 , 8 . Eight of the reported cases, representing four in the mandibular gland and four in the parotid gland, had microscopical findings, although detailed macroscopical descriptions including the findings for the cut surface were only provided in one case 2 .…”

“…Eight of the reported cases, representing four in the mandibular gland and four in the parotid gland, had microscopical findings, although detailed macroscopical descriptions including the findings for the cut surface were only provided in one case 2 . Histologically, lipomatosis was characterized by interstitial fatty infiltration separating the individual glands into groups of various sizes without inflammation and fibrosis 2 , 7 . One case had a thin capsule 2 , and seven other cases did not have a distinct capsule 7 .…”

“…Histologically, lipomatosis was characterized by interstitial fatty infiltration separating the individual glands into groups of various sizes without inflammation and fibrosis 2 , 7 . One case had a thin capsule 2 , and seven other cases did not have a distinct capsule 7 .…”