“…Nanocarriers provide several advantages, such as preventing active drugs from degrading, allowing for higher and more efficient concentrations in the target tissue, and reducing the severity of toxic side effects [16]. The lipid-based nanocarriers have greater importance due to their low toxicity [17], high drug-loading capacity [18], improved bioavailability [19], high biocompatibility [20], high protection from degradation in the gastrointestinal tract (GIT [21], controlled-release behavior [3], ease to scale-up and sterilize [6], easy to validate [2], and also useful for the administration of drugs through different routes [17]. Unique properties like, tailorable surface to apply any targeting strategy, and an improved bio distribution and pharmacokinetic profile makes lipid-based system as a unique approach.…”