Lipid metabolism and apolipoprotein E phenotypes in patients with xanthelasma

Are normolipidaemic patients with xanthelasma prone to atherosclerosis?

“…Studying other risk factors in NPX revealed no abnormalities in BP or blood glucose levels compared with controls, as reported by others. 2,11,15 However, and in accordance with Chan and colleagues, 2 our NPX did have significantly higher BMI compared with controls. The degree of increased IMT in NPX was not related to any of the studied risk factors.…”

Xanthelasma palpebrarum and its relation to atherosclerotic risk factors and lipoprotein (a)

“…Ribera et al . 12 compared 115 patients with xanthelasma with 105 matched controls, and found the prevalence of familial and individual CVD to be significantly higher in patients with xanthelasma. In a controlled study with 113 xanthelasma patients, however, Segal et al .…”

Treatment of Grade I and II types of xanthelasma palpebrarum with intralesional heparin sodium

“…Histologically, xanthelasmata is composed of foam cells laden with cholesterol deposits around dermal capillaries and cutaneous appendages (Mittelviefhaus, Kreusser, Böhringer, & Auw-Hädrich, 2011). The histologic feature of xanthelasma is similar to atherosclerotic plaques, and xanthelasma has been recognized as an extrinsic manifestation of dyslipidoses (Ribera et al, 1995). Xanthelasma can be classified into four grades by clinical manifestation and invasion range of the lesions: Grade I, the lesions involve only the upper eyelids;…”