“…EA also gained considerable support from studies suggesting an increased incidence of terminal limb defects after chorionic villus sampling (Anonymous, 1991;Firth et al, 1991;Hsieh et al, 1991;Lilford, 1991;Mastroiacovo and Pontes Cavalcanti, 1991;Mastroiacovo and Botto, 1992;Burton et al, 1992;Quintero et al, 1992;Mastroiacovo et al, 1993;Firth et al, 1994;Hsieh et al, 1995;Mastroiacovo and Botto, 1996;Firth et al, 1996).…”