Ligand Binding Assays in the 21st Century Laboratory: Automation

Ahene, Ago; Morrow, Chris; Rusnak, David W.; Spitz, Susan; Usansky, Joel; Pils, Holger; Civoli, Francesca; Pandya, Kinnari; Sue, Brian; Leach, Daniel; Derent, John

doi:10.1208/s12248-012-9323-z

Cited by 11 publications

(1 citation statement)

References 7 publications

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“…The automation sub-team provided a comprehensive evaluation of the current state of automation and offered a look into the future [5]. The sub-team believes that automation in the twenty-first century laboratory should take advantage of recent advances in electronics, instrumentation, and programming.…”

Section: Persuasionmentioning

confidence: 99%

Ligand Binding Assays in the 21st Century Laboratory—A Call for Change

Ray

Ahene

2012

AAPS J

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OVERVIEWIn June 2009, a group of ligand binding assay experts met in Seattle, WA to discuss the need for greater efficiency in bioanalytical laboratories. The central premise was increased utilization of technological innovation will lead to increased quality, throughput, and efficiency. Currently, there are very few laboratories that have reached the ideal or utopian level desired. The biggest challenge currently facing the ligand binding community is a reliance on manual processes and paper-based systems, ineffective integration, and a lack of standardization in many areas. In order to address these gaps, we identified speakers who had developed solutions to parts of the overall problem. The event spanned 2 days with participation from three distinct groups: biopharmaceutical companies, contract research organizations, and research equipment providers. The goal was to share best practices, identify gaps, and define next steps. The outcome of the meeting was the development of four sub-teams that included: reagents, instrument platforms, automation, and electronic solutions. Each sub-team was given the task of identifying the most achievable and high-impact facets to change or improve.

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Section: Persuasionmentioning

confidence: 99%