The Application of Immunochromatographic Analysis in Early Detection of Gastric Cancer

Wang, Kan; Cui, Daxiang

doi:10.1007/978-94-024-0951-2_8

Cited by 2 publications

(5 citation statements)

References 115 publications

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“…We have developed a chromatography chip for rapid detection of gastric cancer biomarkers CA72-4 and CEA, and a software system for quantitative analysis of gastric cancer marker detection results based on smartphones [33]. We have achieved quantitative analysis of detection results and automatically uploaded data to cloud management systems and cloud databases, facilitating analysis of home and field detection results.…”

Section: Development Of a Detection System Based On Smartphonesmentioning

confidence: 99%

Advances and Prospects in Integrated Nano-oncology

Jiang,

Cui,

Huang

et al. 2024

Nano Biomedicine and Engineering

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In recent years, the deep integration of basic research and clinical translational research of nanotechnology and oncology has led to the emergence of a new branch, namely integrated nanooncology. This is an emerging and important interdisciplinary field, which plays an irreplaceable role in the diagnosis, treatment, early warning, monitoring and prevention of tumors, and has become a new interdisciplinary frontier. Here main advances of integrated nano-oncology was reviewed, mainly included controlled preparation of nanomaterials, ultra-sensitive detection of tumor biomarkers, multifunctional nanoimaging probes and integrated diagnosis and treatment technology, innovative nano drugs and nano drug delivery system, DNA nanotechnology, RNA nanotechnology, nano selfassembly technology, nanosensors, intelligent nanorobots, nanotherapeutic machines. The terms, concepts, trends and challenges are also discussed with the aim of promoting the application of nanotechnology in integrated oncology and solving the scientific and key technical problems in basic and clinical translational research of cancer.

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Section: Development Of a Detection System Based On Smartphonesmentioning

confidence: 99%

Advances and Prospects in Integrated Nano-oncology

Jiang,

Cui,

Huang

et al. 2024

Nano Biomedicine and Engineering

Self Cite

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“…They are used for the determination of ABO and rhesus blood groups, for HLA tissue grouping, for the immunolabeling of acute leukemia and for the development of immunological tests (enzyme-linked immunosorbent assay (ELISA), lateral flow immunoassay (LFIA), radioimmunoassay (RIA), etc.) [ 18 , 19 , 20 , 21 , 27 , 31 , 55 , 56 , 57 , 58 , 59 , 60 ]. Other Abs issued from animals conjugated to markers or enzymes are used for diagnostic kits manufacturing, immunocytochemical analysis, and research [ 18 , 19 , 20 , 21 , 27 , 31 , 55 , 56 , 57 , 58 , 60 , 61 , 62 ].…”

Section: Performances Of An Antibodymentioning

confidence: 99%

“…Moreover, a panel of mAbs is usually used to map and study the role of epitopes in certain cellular functions and mechanisms. They have also an important role in proteomics and mass biological screening tests [ 18 , 19 , 20 , 21 , 31 , 43 , 55 , 56 , 58 , 59 ]. In general, mAbs are used in diagnostic, agri-food, veterinary, microbiological, and toxicological tests [ 20 , 21 , 31 , 56 , 58 , 63 ].…”

Section: Performances Of An Antibodymentioning

confidence: 99%

“…Their quantifications are then carried out using UV, electrochemical, or fluorescence detectors. The GC-MS or, even more, LC-MS, are the most efficient methods of analysis [ 11 , 16 , 18 , 19 ]. However, they are expensive and require trained and qualified clinicians to conduct the analyses.…”

Section: Introductionmentioning

confidence: 99%

“…However, they are expensive and require trained and qualified clinicians to conduct the analyses. Every year—in order to simplify detection methods and reduce costs—new lateral flow immunoassay (LFIA) tests appear in all fields of medicine, including cancerology, toxicology, and infectology [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ], to be used directly in places where patients are cared for, with no specialized laboratories. The goal is to have immediate results, so that certain diagnoses can be quickly included or excluded.…”

Section: Introductionmentioning

confidence: 99%

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Monoclonal Antibodies Application in Lateral Flow Immunochromatographic Assays for Drugs of Abuse Detection

et al. 2021

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Lateral flow assays (lateral flow immunoassays and nucleic acid lateral flow assays) have experienced a great boom in a wide variety of early diagnostic and screening applications. As opposed to conventional examinations (High Performance Liquid Chromatography, Polymerase Chain Reaction, Gas chromatography-Mass Spectrometry, etc.), they obtain the results of a sample’s analysis within a short period. In resource-limited areas, these tests must be simple, reliable, and inexpensive. In this review, we outline the production process of antibodies against drugs of abuse (such as heroin, amphetamine, benzodiazepines, cannabis, etc.), used in lateral flow immunoassays as revelation or detection molecules, with a focus on the components, the principles, the formats, and the mechanisms of reaction of these assays. Further, we report the monoclonal antibody advantages over the polyclonal ones used against drugs of abuse. The perspective on aptamer use for lateral flow assay development was also discussed as a possible alternative to antibodies in view of improving the limit of detection, sensitivity, and specificity of lateral flow assays.

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The Application of Immunochromatographic Analysis in Early Detection of Gastric Cancer

Cited by 2 publications

References 115 publications

Advances and Prospects in Integrated Nano-oncology

Advances and Prospects in Integrated Nano-oncology

Monoclonal Antibodies Application in Lateral Flow Immunochromatographic Assays for Drugs of Abuse Detection

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