Less than Adequate Vitamin D Status and Intake in Latin America and the Caribbean: A Problem of Unknown Magnitude

Brito, Alex; Cori, Héctor; Olivares, Manuel; Mujica, Maria Fernanda; Cediel, Gustavo; Romaña, Daniel López de

doi:10.1177/156482651303400107

Cited by 65 publications

(57 citation statements)

References 51 publications

(52 reference statements)

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“…7 The size of this problem in children and adolescents in Latin America is unknown; only Mexico has representative data at a national level that show a 54% and 28% prevalence of VD deficiency and insufficiency in preschoolers and school children, r e s p e c t i v e l y . 8 A r g e n t i n a h a s representative data available for the Patagonia region in children aged 6-23 months, who had a mean 25(OH) D serum level of 67.5 nmol/L (95% confidence interval [CI]: 65.3-69.8), with extreme values ranging from 10.5 to 177.5 nmol/L. As observed, values for the provinces assessed i n t h e m o n t h s c l o s e r t o w i n t e r (Chubut, Neuquén, and Santa Cruz) are significantly lower than in those assessed in November and December (Río Negro, Tierra del Fuego, and La Pampa).…”

Section: Vitamin D Deficiency In Children and Adolescentsmentioning

confidence: 99%

Vitamin D deficiency in pediatric clinical practice

Cediel¹,

Pacheco-Acosta

CastiUo-Durdn

2018

Arch Argent Pediatr

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Vitamin D research suggests it has a role in disorders other than bone metabolism. Objective: To update the information on vitamin D deficiency (VDD) in pediatric clinical disorders. Methods: Search in virtual libraries, giving priority to clinical and longitudinal studies and meta-analyses on VDD in the pediatric age group published in the past 20 years. The terms "vitamin D deficiency", "children and adolescents" (both in Spanish and English) were used as search descriptors. Results:In the pediatric population, VDD is associated with different clinical diseases, such as bone alterations, insulin resistance, metabolic syndrome, respiratory tract infections, asthma, and autoimmune diseases. Besides, it is associated with prematurity, obesity, malabsorption, use of anticonvulsant agents, and lifestyle characteristics, such as clothing, extreme latitudes, low consumption, and little sun exposure. Conclusions: According to the evidence, VDD is highly prevalent in several disorders and diseases in the pediatric age group. The recommendation is to prevent VDD in risk conditions and to maintain 25(OH)D serum levels > 75 nmol/L.

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Section: Vitamin D Deficiency In Children and Adolescentsmentioning

confidence: 99%

Vitamin D deficiency in pediatric clinical practice

Cediel¹,

Pacheco-Acosta

CastiUo-Durdn

2018

Arch Argent Pediatr

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“…Entretanto, alguns estudos 56,57,58 têm mostrado que tais estimativas de ingestão são difíceis de serem alcançadas apenas com a dieta.…”

Section: Prevenção Da Deficiência De Vitamina Dunclassified

Vitamina D em pediatria

Almeida¹,

Nogueira‐de‐Almeida²,

Ferraz³

2018

Int J Nutrol

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A vitamina D (VD) é uma das vitaminas lipossolúveis. Suas principais fontes na natureza são a dieta e a produção endógena mediada pela exposição à luz solar. Descobertas recentes mostraram que outros órgãos, que não o rim e o fígado, são também capazes de sintetizar a VD metabolicamente ativa (calcitriol). A deficiência de vitamina D (DVD) foi descrita há quase 2.000 anos e é classicamente relacionada às doenças do sistema ósteo-muscular (em especial, raquitismo e osteomalácia). Adicionalmente nos últimos anos, a DVD tem sido associada à desordens que acometem outros sistemas do organismo, como, por exemplo, asma e diabetes. Além disso, tem sido observada uma elevação da prevalência da DVD em todo o mundo, mesmo em países com boas condições de insolação. A forma mais adequada de prevenção da DVD se dá pela suplementação vitamínica já que não há limites seguros para a exposição solar. O tratamento da DVD baseia-se, principalmente, na reposição da vitamina e está indicado nas formas sintomáticas (sintomas ósteo-musculares) da carência. A intoxicação pela VD é rara e observada em lactentes e crianças jovens que ingerem doses elevadas de VD de forma aguda. Este artigo de revisão aborda estas e outras questões a respeito da VD, com ênfase especial às particularidades relacionadas às crianças e aos adolescentes. Palavras-chave:Colecalciferol. Lactente. Vitamina D. ABSTRACTVitamin D (VD) is one of the fat-soluble vitamins. Its main sources in nature are diet and exposure to sunlight. Recent findings have shown that organs other than the kidney and liver are also able to synthesize VD metabolically active (calcitriol). Vitamin D deficiency (VDD) has been described almost 2.000 years ago and is classically related to diseases of the musculoskeletal system (especially rickets and osteomalacia). However, in recent years, VDD has been linked to disorders that affect other systems in the body, such as asthma and diabetes. In addition, an increase in the prevalence of VDD worldwide has been observed, even in countries with good insolation conditions. The most appropriate way to prevent VDD is by vitamin supplementation since there are no safe limits to sun exposure.

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“…7 La magnitud del problema en niños y adolescentes en América Latina es desconocida; solo México presenta datos representativos nacionales, que muestran entre un 54% y un 28% de prevalencia de déficit/insuficiencia de VD en preescolares y escolares, respectivamente. 8 Argentina presenta datos representativos en la región de la Patagonia en niños entre los 6 y los 23 meses, que muestran una concentración media de 25(OH)D sérica de 67,5 nmol/L (IC 95%: 65,3-69,8), con valores extremos entre 10,5 y 177,5 nmol/L. Según se observa, los valores correspondientes al grupo de provincias relevadas en los meses más próximos al invierno (Chubut, Neuquén y Santa Cruz) son significativamente más bajos que en aquellas relevadas entre los meses de noviembre y diciembre (Río Negro, Tierra del Fuego y La Pampa).…”

Section: Deficiencia De Vitamina D En Niños Y Adolescentesunclassified

“…Según se observa, los valores correspondientes al grupo de provincias relevadas en los meses más próximos al invierno (Chubut, Neuquén y Santa Cruz) son significativamente más bajos que en aquellas relevadas entre los meses de noviembre y diciembre (Río Negro, Tierra del Fuego y La Pampa). 9 Algunos países han reportado prevalencia de DVD en niños con muestras no representativas, tales como Colombia del 10-12% (< 50 nmol/L), Brasil del 9% (< 50 nmol/L) 8 y, recientemente, Chile del 64% (< 50 nmol/L) en preescolares de zonas australes (> 45º 35` S). 10 Esta evidencia sugiere una alta prevalencia de deficiencia e insuficiencia de VD en la región en niños y adolescentes, especialmente, durante el invierno y en latitudes extremas.…”

Section: Deficiencia De Vitamina D En Niños Y Adolescentesunclassified

Deficiencia de vitamina D en la práctica clínica pediátrica

2018

Arch Argent Pediatr

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Less than Adequate Vitamin D Status and Intake in Latin America and the Caribbean: A Problem of Unknown Magnitude

Abstract: There is some indication that vitamin D insufficiency may be a public health problem in Latin America and the Caribbean, but the exact magnitude is currently unknown.

Cited by 65 publications

References 51 publications

Vitamin D deficiency in pediatric clinical practice

Vitamin D deficiency in pediatric clinical practice

Vitamina D em pediatria

Deficiencia de vitamina D en la práctica clínica pediátrica

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