Les cancers du sein au Gabon : aspects épidémiologique, diagnostique et thérapeutique

Mayi-Tsonga, S.; Belembaogo, E.; Meye, Jean‐François; Ngou-Mve-Ngou, JP; Nguizi-Ogoula, S.; Bisse, A.

doi:10.1007/s12558-008-0003-y

Cited by 7 publications

(5 citation statements)

References 7 publications

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“…The presentation time in our study was long in the majority of cases 76%, with an average of 7.01 ± 1.048 months. Other studies also found a long delay with an average delay of 13 ± 8 months [29].…”

Section: Discussionmentioning

confidence: 81%

Breast Cancer: Epidemiological, Clinical, and Therapeutic Aspects in Pointe Noire (Congo Brazzaville)

Ngatali¹,

Liboko²,

Ndounga³

et al. 2019

OJPathology

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Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. The objective of our study was to describe the epidemiological, clinical and therapeutic aspects of breast cancer at the General Hospital of Loandjili in Pointe Noire. Patients and Methods: This was a descriptive and cross-sectional study that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January 1st, 2012 to December 31st, 2016 for duration of 5 years. 54 records of patients over 18 years of age with histological evidence were collected. The variables studied were: age, level of education, time to presentation, telltale sign, stage of extension, histological type, and histological grade. Chi-square test was used to compare variables and groups. Results: At the end of this study, we collected 54 files of breast cancer patients from 150 patients hospitalized in the Cancer Department. The frequency of breast cancer was 36%. The average age was 50 ± 13.6 years; the extremes were 27 years and 79 years. The most represented age group was from 37 to 40 years old with a percentage of 28%. The patient's level of study was primary in the majority of cases (57%). The most represented histological type was invasive ductal carcinoma, (100%). The majority of patients arrived at advanced stages 44.4% and metastatic stages 26%. Patients were treated in most of cases by chemotherapy (82%), surgery (42%) and radiotherapy (10%). There was a correlation between time of presentation and stage of extension. Conclusion: Breast cancer is the first cancer of the woman in Pointe Noire. Patients arrive at advanced stages; the most common histological type is invasive ductal carcino-

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Section: Discussionmentioning

confidence: 81%

Breast Cancer: Epidemiological, Clinical, and Therapeutic Aspects in Pointe Noire (Congo Brazzaville)

Ngatali¹,

Liboko²,

Ndounga³

et al. 2019

OJPathology

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“…On the other hand, other European studies have found a much older average age, in older women, such as those by Mousseau M. et al [15]; Colombié M. [13] reported an average age of 61, and Mayi T. [25] also found an average age of onset of 60.…”

Section:  Agementioning

confidence: 89%

Place of Bone Scintigraphy in the Assessment of Extension and Follow-Up of Breast Cancer in Senegal: Study of 165 Cases in the Nuclear Medicine Department of Idrissa Pouye General Hospital (Dakar)

Bathily,

Djigo,

et al. 2024

OJMI

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Introduction: Breast cancer is the most common cancer in women worldwide, accounting for an estimated 22% of all female cancers. It is the leading cause of cancer mortality in women, almost all of which is due to metastases, with 73% of metastases occurring in the bone. In oncology, metastable technetium 99-labelled methylene bisphosphonate bone scintigraphy (BS) remains the standard examination for detecting and assessing the extent of bone metastases. The aim of this study was to assess the role of BS in the evaluation and follow-up of breast cancer in Senegal. Methodology: This was a retrospective study of breast cancer patients who underwent bone scintigraphy with 99m Tc-HMDP in the nuclear medicine department of Idrissa Pouye General Hospital (IPGHO), from July 2009 to June 2022. Results: We enrolled 165 patients, mean age 46.79 years (27 -87 years). BS was performed in 94.37% of cases for post-therapeutic monitoring and in 5.63% for pre-therapeutic assessment. Results were contributory in 131 patients (92.25%), of whom 72 cases (50.70%) were normal and 59 cases (41.55%) positive or presenting bone metastases; and non-contributory or doubtful in 11 cases (7.75%). Secondary bone locations were multiple in 57 cases (96.61%) and single or solitary in 2 cases (3.

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“…Dans notre pratique, le protocole FAC reste le plus utilisé compte tenu de son faible coût et de sa disponibilité. Notre étude permet de retenir un regain d'intérêt pour la chimiothérapie postopéra-toire pour les patientes chez qui l'évolution de la maladie ne permet pas d'attendre ou de poursuivre la chimiothérapie néo-adjuvante [5]. Cette attitude semble logique, l'exérèse tumorale diminuant la prolifération des cellules tumorales à partir de la tumeur cancéreuse, malgré le risque théorique d'une libération des cellules tumorales par voie hématogène liée à l'anesthésie et à la chirurgie [6,7].…”

Section: Commentairesunclassified

“…Ces décès sont dus aux formes avancées ou inflammatoires qui représentent 30 à 50 % des nouveaux cas [4][5]. La prise en charge de ces formes repose sur le concept actuel de maladie générale reconnue actuellement aux cancers du sein [6][7].…”

Section: Introductionunclassified

Chimiothérapie néoadjuvante et cancers du sein avancés ou inflammatoires à Yaoundé (Cameroun)

et al. 2011

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Le but de cette étude était de relever les facteurs limitant la pratique de la chimiothérapie néoadjuvante dans le traitement des cancers du sein avancés ou inflammatoires en milieu africain au sud du Sahara. Il s'agit d'une étude prospective transversale dans laquelle l'équipe médicale s'était proposée d'administrer une chimiothérapie avant le traitement de tous les cancers du sein avancés ou inflammatoires venus pour traitement chirurgical. Sur les 35 malades incluses, la chimiothérapie néoadjuvante avait été refusée d'emblée par 6 patientes (17,14 %), prescrite chez 29 malades (88,8 % des cas), administrée chez 10 patientes (28,57 %), interrompue chez 11 patientes (31,4 % des cas) pour cause de coût élevé, d'effets néfastes ou de durée longue. Elle n'avait pas été débutée pour évolution rapide de la tumeur dans six cas. L'étude recommande une prescription optionnelle de la chimiothérapie néoadjuvante, en milieu africain subsaharien, aux malades présentant un cancer avancé ou inflammatoire du sein, en tenant compte des limites de cette thérapie, des formes cliniques à évolution rapide et du consentement des patientes. Pour citer cette revue : J. Afr. Cancer 3 (2011). Mots clés Cancer du sein avancé · Chimiothérapie néoadjuvante · Afrique subsaharienneAbstract The aim of this study was to evaluate the limiting factors in the practice of neoadjuvant chemotherapy in the treatment of advanced or inflammatory breast cancer in an African sub-Saharan context. In this prospective crosssectional study, the medical team had proposed to administer neoadjuvant chemotherapy to all patients presenting with an operable advanced or inflammatory breast cancer. Out of 35 female patients retained, 6 patients (17.14%) refused to undergo preoperative chemotherapy. Twenty-nine patients were prescribed for neoadjuvant chemotherapy (88.8%). The treatment was administered to 10 patients (28.57%), and it was interrupted in 11 cases (31.4%) because of cost, side effects or long duration. The treatment was not started in six patients because of a rapid growth of the tumour. The study recommends an optional prescription of neoadjuvant chemotherapy to African patients presenting with an advanced or inflammatory breast cancer, taking into account the limitations of the therapy, the clinical stage of the tumour and consent of the patients. To cite this journal: J. Afr. Cancer 3 (2011).

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Les cancers du sein au Gabon : aspects épidémiologique, diagnostique et thérapeutique

Cited by 7 publications

References 7 publications

Breast Cancer: Epidemiological, Clinical, and Therapeutic Aspects in Pointe Noire (Congo Brazzaville)

Breast Cancer: Epidemiological, Clinical, and Therapeutic Aspects in Pointe Noire (Congo Brazzaville)

Place of Bone Scintigraphy in the Assessment of Extension and Follow-Up of Breast Cancer in Senegal: Study of 165 Cases in the Nuclear Medicine Department of Idrissa Pouye General Hospital (Dakar)

Chimiothérapie néoadjuvante et cancers du sein avancés ou inflammatoires à Yaoundé (Cameroun)

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