Leptospira spp. In Commensal Rodents, Beijing, China

Wang, Chengmin; He, Hongxuan

doi:10.7589/2012-10-261

Cited by 16 publications

(25 citation statements)

References 5 publications

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“…Giant pandas are currently restricted to the Qinling, Minshan, Qionglai, Daxiangling, Xiaoxiangling and Liangshan Mountains on the Eastern edge of the Tibetan plateau, and number about 1,600 individuals, of which 17.23% are in Qinling, 44.36% in Minshan and 27.38% in Qionglai [4,5]. Baylisascaris schroederi is one of the most common nematodes of giant panda, and can cause severe baylisascarosis in both wild and captive giant pandas [1,2,6]. The parasite mainly lives in the small intestine of the giant panda.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of the genetic diversity of the nematode parasite Baylisascaris schroederi from wild giant pandas in different mountain ranges in China

et al. 2013

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BackgroundBaylisascaris schroederi is one of the most common nematodes of the giant panda, and can cause severe baylisascarosis in both wild and captive giant pandas. Previous studies of the giant pandas indicated that this population is genetically distinct, implying the presence of a new subspecies. Based on the co-evolution between the parasite and the host, the aim of this study was to investigate the genetic differentiation in the B. schroederi population collected from giant pandas inhabiting different mountain ranges, and further to identify whether the evolution of this parasite correlates with the evolution of giant pandas.MethodsIn this study, 48 B. schroederi were collected from 28 wild giant pandas inhabiting the Qinling, Minshan and Qionglai mountain ranges in China. The complete sequence of the mitochondrial cytochrome b (mtCytb) gene was amplified by PCR, and the corresponding population genetic diversity of the three mountain populations was determined. In addition, we discussed the evolutionary relationship between B. schroederi and its host giant panda.ResultsFor the DNA dataset, insignificant Fst values and a significant, high level of gene flow were detected among the three mountain populations of B. schroederi, and high genetic variation within populations and a low genetic distance were observed. Both phylogenetic analyses and network mapping of the 16 haplotypes revealed a dispersed pattern and an absence of branches strictly corresponding to the three mountain range sampling sites. Neutrality tests and mismatch analysis indicated that B. schroederi experienced a population expansion in the past.ConclusionsTaken together, the dispersed haplotype map, extremely high gene flow among the three populations of B. schroederi, low genetic structure and rapid evolutionary rate suggest that the B. schroederi populations did not follow a pattern of isolation by distance, indicating the existence of physical connections before these populations became geographically separated.

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Section: Introductionmentioning

confidence: 99%

“…schroederi larvae are sometimes also recovered post-mortem from the liver, lungs, heart or brain, which is associated with an increased clinical severity and pathologic manifestations, making B . schroederi one of the most serious parasites of giant panda [2]. …”

Section: Introductionmentioning

confidence: 99%

Analysis of the genetic diversity of the nematode parasite Baylisascaris schroederi from wild giant pandas in different mountain ranges in China

et al. 2013

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“…and anti-T. gondii antibodies in rodents from different worldwide locations (COLA et al, 2010;HALLIDAY et al, 2013;JITTAPALAPONG et al, 2011;LILENBAUM, 2013;MERCIER et al, 2013;MGODE et al, 2014;RUFFOLO, 2008;SPOHR, 2009;VUJANIĆ et al, 2011;WANG;HE, 2013).…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of leptospirosis in rodents, as determined by the level of antibodies raised in response to different serovars, ranges from 3.33% to 30.2% in different countries (AGUDELO-FLÓREZ et al, 2009;FELT et al, 2011;GAROUSSI et al, 2006;HALLIDAY et al, 2013;LILENBAUM, 2013;MGODE et al, 2014;MOHAMED et al, 2010;SPOHR, 2009;WANG;HE, 2013). In Brazil, leptospirosis positivity rates of 9.3% and 17% were detected in Paraná (PR) (SPOHR, 2009) and Rio de Janeiro (MARTINS; LILENBAUM, 2013), respectively.…”

Section: Introductionmentioning

confidence: 99%

A serological survey of agents causing leptospirosis and toxoplasmosis in Rattus rattus in the city of Umuarama, northwest Paraná, Brazil

Lopes

Germano

Gerônimo

et al. 2017

SCA

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Synanthropic rodents, present in both urban and rural areas, are responsible for the zoonotic transmission of several diseases to humans as well as for significant economic losses. They act as reservoirs for important viral diseases, bacterial diseases such as leptospirosis, and parasitic diseases such as toxoplasmosis and leishmaniasis. The aim of the present study was to assess the seropositivity of synanthropic rodents in Umuarama city, located in the northwestern region of Paraná State, Brazil, to agents causing leptospirosis and toxoplasmosis. The microscopic agglutination technique (MAT) was used to detect anti-Leptospira antibodies, and the indirect immunofluorescence reaction (IIFR) was used to detect anti-Toxoplasma gondii antibodies. Of 178 animals collected, four (2.24%) were seropositive for Leptospira spp. and ten (5.62%) for Toxoplasma gondii. Ninety-five (53.38%) of the collected animals were male and 83 (46.62%) were female, and two (1.23%) originated from urban areas while 176 (98.87%) originated from peri-urban areas. Serological results showed that the synanthropic rodents examined here had low seroreactivity for agents causing both leptospirosis and toxoplasmosis, in both urban and peri-urban regions of Umuarama city. This could be associated with the high Human Development Index for the study area. However, preventative measures must continue to be observed, as rodents are important reservoirs for, and disseminators of, disease causing agents. ResumoOs roedores sinantrópicos determinam grandes prejuízos econômicos, e são responsáveis pela transmissão de várias zoonoses ao homem tanto em áreas urbanas quanto nas rurais, atuando como reservatórios de importantes doenças que incluem a leptospirose, toxoplasmose, leishmaniose e algumas de etiologia viral. O presente trabalho investigou a sororeatividade para leptospirose e toxoplasmose em roedores sinantrópicos da cidade de Umuarama, cidade localizada na região noroeste do estado do Paraná, Brasil. A técnica Soroaglutinação Microscópica (SAM) foi utilizada para a detecção de anticorpos anti-Leptospira spp e a Reação de Imunofluorescência Indireta (RIFI) para a detecção de anticorpos anti-Toxoplasma gondii. Dos 178 animais examinados, quatro (2,24%) foram reagentes para Leptospira spp. e 10 (5,62%) para o Toxoplasma gondii. Destes animais, 95 (53,38%) eram machos e 83 (46,62%) fêmeas, dois (1,23%) eram provenientes da área urbana e 176 (98,87%) da área periurbana. Os resultados obtidos demonstraram que os roedores sinantrópicos examinados apresentaram baixa freqüência de sororeatividade para as duas zoonoses investigadas, tanto na região urbana como na periurbana da cidade de Umuarama, fato que pode estar associado ao alto Índice de Desenvolvimento Humano encontrado, contudo, as medidas preventivas devem ser mantidas, pois os roedores são importantes elos na cadeia epidemiológica das doenças analisadas.

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“…R. tanezumi atau sering disebut dengan tikus rumah dikenal sebagai tikus komensal karena seluruh aktivitas hidupnya dilakukan di dalam rumah (Khariri, 2019). Jenis tikus ini merupakan reservoir utama leptospirosis selain R. norvegicus dan Mus musculus (Wang & He, 2013).…”

Section: Pembahasanunclassified

Analisis Faktor Lingkungan Terhadap Distribusi Jenis Tikus Yang Terkonfirmasi Sebagai Reservoir Leptospirosis Di Tiga Kabupaten Di Provinsi Sumatera Selatan

Supranelfy¹,

Oktarina

2019

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The role of rats as a potential reservoir of the disease remains negative impacts on the routine life, safety, welfare and economic communities. Rattus tanezumi, R. norvegicus, R. exulans, R. hoffmani, R. argentiventer and Maxomys bartelsi have been confirmed as leptospirosis reservoirs in Indonesia. Some rat species suspected as leptospirosis reservoirs were reported in Lahat, Banyuasin and Ogan Komering Ilir (OKI) districts. It puts those three districts on high risk of leptospirosis transmission in the community. The aim of the study was to identify the environmental factors associated with the distribution of the leptospirosis-confirmed rats in the three districts of South Sumatera Province. Data used in this study were obtained from surveillance of the Specific Research on Vector and Reservoir Diseases Special Research" (Rikhus Vektora) conducted in 2015. A total of 308 captured rats was tested for leptospirosis using MAT and PCR methods. The environmental variables were recorded during the surveillance. Data were analysed using chi-square. The laboratory results demonstrated that 44 of 308 rats captured in the three districts were positive for leptospirosis. In addition, there was a significant correlation between the distribution of the positive leptospirosis-confirmed rats with ecosystem variables, trap location, altitudes and temperature. However, they were not correlated to the weather variables and pH. Unfortunately, the topographic variables could not be analysed because all rats were found in the lowlands. The early warning of leptospirosis transmission should be addressed to the three districts due to the presence of the positive leptospirosis-confirmed rats in those areas.

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Leptospira spp. In Commensal Rodents, Beijing, China

Cited by 16 publications

References 5 publications

Analysis of the genetic diversity of the nematode parasite Baylisascaris schroederi from wild giant pandas in different mountain ranges in China

Analysis of the genetic diversity of the nematode parasite Baylisascaris schroederi from wild giant pandas in different mountain ranges in China

A serological survey of agents causing leptospirosis and toxoplasmosis in Rattus rattus in the city of Umuarama, northwest Paraná, Brazil

Analisis Faktor Lingkungan Terhadap Distribusi Jenis Tikus Yang Terkonfirmasi Sebagai Reservoir Leptospirosis Di Tiga Kabupaten Di Provinsi Sumatera Selatan

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