Leisure-Time Physical Activity and Its Association With Metabolic Risk Factors in Iranian Adults: Tehran Lipid and Glucose Study, 2005–2008

Abstract

We examined the association between leisure-time physical activity (LTPA) and metabolic syndrome (MetS) among 4,665 randomly selected adults who participated in the Tehran Lipid and Glucose Study, 2005–2008. Normal-weight participants with light LTPA had higher risk of low high-density lipoprotein cholesterol and elevated levels of triglycerides than those with vigorous LTPA. Overweight adults with moderate LTPA had higher risk of having elevated levels of fasting blood glucose than adults with vigorous LTPA and, in the same group, we found an inverse association between light LTPA and MetS after adjustment for sex, age, education levels, smoking, and calorie intake. Although participants in the normal-weight and obese groups with vigorous LTPA had higher risk of high systolic blood pressure than participants with moderate LTPA, this finding had no clinical significance. Increased LTPA is associated with decreased risk of any damaging changes in the markers of MetS.

Helicobacter pylori is associated with dyslipidemia but not with other risk factors of cardiovascular disease

“…However, we evaluated the association between H. pylori seropositivity and the cardiometabolic risk factors, paying particular attention to careful control for known risk factors and confounders including age, sex, smoking status, alcohol consumption, socioeconomic status, physical activity, and body mass index. Physical inactivity and obesity are established risk factors of metabolic syndrome and cardiovascular disease353637. The current study provides evidence that H. pylori infection is associated with dyslipidemia such as higher total cholesterol and LDL-C, as well as lower HDL-C, regardless of potential confounders and putative risk factors.…”

Dyslipidemia patterns are differentially associated with dietary factors

“…Several cross-sectional studies in Western populations found that subjects who were more physically active had higher HDLC [33] and lower TG concentrations [34]. Findings from Korean adults [35] and Iranian adults [36] also showed that the amount and intensity of physical activity were positively associated with concentrations of TG or HDLC. One meta-analysis of randomized controlled trials reported that regular aerobic exercise significantly increased HDLC [37].…”

Prevalence of metabolic syndrome and its risk factors among rural adults in Nantong, China

“…The role of LPA in MS is still inconclusive. One previous study identified that an inverse association between light LPA and MS in overweight adults, and light- or moderate-intensity LPA have higher risk of MS than vigorous-intensity LPA in normal-weight adults35. A meta-analysis with 10-years follow-up study reported that a 29 and 32% lower risk of MS in men and women associated with the highest levels of LPA, but a weaker association between MS and moderate LPA in men, compared with those in the lowest levels of LPA36.…”