Leishmania infantum DNA detected in phlebotomine species from Puerto Iguazú City, Misiones province, Argentina

Moya, Sofía Lorián; Giuliani, Magalí Gabriela; Santini, María Soledad; Quintana, María Gabriela; Salomón, Oscar Daniel; Liotta, Domingo Javier

doi:10.1016/j.actatropica.2017.05.004

Cited by 21 publications

(12 citation statements)

References 31 publications

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“…longipalpis and 1 Mi. quinquefer) without a visible blood meal inside, captured in the same site as the previously infected ones suggesting the presence of a "hot spot" of parasites [71].…”

Section: Sitementioning

confidence: 81%

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Multiscale environmental determinants of Leishmania vectors in the urban-rural context

et al. 2020

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Background In South America, cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL) are emerging diseases, expanding in the border area of Argentina, Brazil and Paraguay. Outbreaks of CL were reported since the 1990s, with Nyssomyia whitmani as the main vector in this region. Regarding VL, urban reports started in 2010 with Lutzomyia longipalpis as the main vector. The aim of this study was to evaluate environmental determinants related to the main vectors of leishmaniasis, to contribute to the prevention and control response to the emergence of VL and CL in the Argentina-Brazil-Paraguay border region. Methods The cross-sectional survey includes two cities and two close rural areas in the Argentinean Northeast Region, between November 2014 and January 2015, with a total of 95 sampling sites. REDILA-BL traps were set for three consecutive nights, and a total of 68 meso- and microscale environmental and landscape characteristics were surveyed. The association between vector abundance with different variables was evaluated using a generalized linear model with zero-inflated negative binomial distribution. We analyzed females for detection of Leishmania DNA. Results The analysis for Lu. longipalpis indicates an excess of absences when the mean NDWI around the sites were higher. The abundance of Lu. longipalpis at mesoscale level was higher when more urban services were present, and when blood sources such as chickens or dogs at the microscale level were present. For Ny. whitmani, no variable was found to be associated with the absences, while its abundance increased in association with the following variables: percentage of tree cover, presence of garbage collection service, hosted people and, at microscale, the presence of poultry. Leshmania infantum DNA was detected in 2/49 (4%) Lu. longipalpis. Conclusions The abundance of both species is influenced by variables at different scales, their influence probably has a hierarchy and they are acting on different aspects of the biology of these vectors. The urban spatial segregation of Lu. longipalpis and the peri-urban and rural segregation of N. whitmani increase the risk of VL and CL. The selection of the better variables for each scale will allow the design of appropriate control strategies depending on species.

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“…longipalpis and 1 Mi. quinquefer) without a visible blood meal inside, captured in the same site as the previously infected ones suggesting the presence of a "hot spot" of parasites [71].…”

Section: Sitementioning

confidence: 81%

“…quinquefer) but only Mg. migonei was suggested a role as permissive vector of Le. infantum in Argentina and Brazil [10,29,[70][71][72] or as a link between urban and wild cycles of ACL [4,45,73]. In the season that followed this study (March 2015) Le.…”

Section: Sitementioning

confidence: 99%

Multiscale environmental determinants of Leishmania vectors in the urban-rural context

et al. 2020

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“…longipalpis, is absent, as well as the finding of other sand flies naturally infected with this agent have suggested that there are other vectors in Latin America (Table 2) (de Araújo-Pereira et al, 2010;Belo et al, 2013b;Bejarano et al, 2001;Carvalho et al, 2010;Feliciangeli et al, 1999;Galvis-Ovallos et al, 2017;González et al, 2014;Guimarães et al, 2016;Lainson and Rangel, 2005;Missawa et al, 2011;Moya et al, 2015Moya et al, , 2017Paternina-Gómez et al, 2013;Pita-Pereira et al, 2008;Rodrigues et al, 2016;Romero and Boelaert, 2010;Salomón et al, 2010;Travi et al, 1990;Zerpa et al, 2003); however, for only some of them has vectorial capacity been proven (Saraiva et al, 2009(Saraiva et al, , 2010).…”

Section: Accepted Manuscriptmentioning

confidence: 99%

“…Lutzomyia species in the domestic environment, changing the epidemiological profile of the disease (Maroli et al, 2013). Table 2 presents some of the proven or suspected vectors of CL in Latin America, based on data found in the literature (Aguilar et al, 1984;Brilhante et al, 2015;Camargo-Neves et al, 2002;Calvopina et al, 2004;Córdoba-Lanús et al, 2006;Feliciangeli et al, 1994Feliciangeli et al, , 2004Guimarães-e-Silva et al, 2017;Kato et al, 2005;Lana et al, 2015;Lara-Silva et al, 2015;Llanos-cuentas et al, 1999;Maroli et al, 2013;Martinez et al, 1999;Moya et al, 2017;Nunes et al, 1991;Paiva et al, 2010;Pech-May et al, 2010;Pita-Pereira et al, 2005Rabinovich et al, 2004;Rangel and Lainson, 2009;Rêgo et al, 2015;Reithinger and Davies 1999;Rowton et al, 1991Rowton et al, ,1992Salomón et al, 2008b;Saraiva et al, 2009;Soccol et al, 2009;Vélez et al, 2012;Vexenat et al, 1986). It is interesting to note that some Lutzomyia spp.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Current status and management of canine leishmaniasis in Latin America

Marcondes

Day

2019

Research in Veterinary Science

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Latin America encompasses diverse geographical, cultural and socioeconomic conditions, which are reflected in the challenges for infectious disease control in the region. One of the most significant regional infectious diseases for humans and domestic dogs is leishmaniasis, occurring as visceral leishmaniasis (VL) caused by Leishmania infantum (syn. L. chagasi) transmitted by sand flies (Lutzomyia longipalpis) and with a canine reservoir, and the more common cutaneous leishmaniasis (CL) involving multiple Leishmania spp. (particularly L. braziliensis), sand fly vectors and reservoir hosts. VL is spreading within Latin America for reasons related to mass migration of human and canine populations, with incursion into novel environments (e.g. related to deforestation) coupled with a background of poverty and poor public health infrastructure. The challenges for control of VL also include: (1) the accurate identification of infected dogs (particularly subclinically infected dogs) with the current reliance on serological rather than molecular diagnostic methods, (2) controversy surrounding the ethics and efficacy of culling of seropositive dogs, (3) the limited efficacy of currently available canine vaccines and their potential to interfere with interpretation of serological testing, (4) the expense associated with distribution of insecticidal dog collars, which may prove to be the most valuable control method, and (5) the cost and therefore accessibility of licensed medical treatment for canine leishmaniasis by the general population. Resolution of these isssues will necessitate a 'One Health' approach to coordination of resources between human and veterinary healthcare.

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“…Migonemyia migonei was found in very low abundance, but it is a species of epidemiological importance, which has been recently defined by Guimarães et al (2016) In addition to being considered a vector of L. (V.) braziliensis in various regions of Brazil, the 3rd epidemiologically important species, Ny. whitmani, was one of the least abundant species found in the parks; it is noteworthy for its probable involvement in the transmission of L. infantum and was recently found infected by L. (V.) guyanensis (Floch 1954) (Moya et al 2017, Souza et al 2017.…”

mentioning

confidence: 99%

Occurrences of Phlebotomine Sand Flies (Diptera: Psychodidae) Potentially Associated with Leishmaniasis Transmission in Urban Parks in the City of São Paulo, Brazil

Lavitschka

Ceretti-Júnior

Marrelli

2018

Journal of the American Mosquito Control Association

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A study of the phlebotomine sand flies was carried out between October 2011 and June 2013 in municipal parks in the city of São Paulo. A total of 173 specimens of 5 species were collected (Psychodopygus lloydi, Pintomyia fischeri, Lutzomyia amarali, Nyssomyia whitmani, and Migonemyia migonei). Three of these species may be involved in the transmission of the causative agent of tegumentary leishmaniasis. Surveillance and monitoring phlebotomine species from these areas are crucial as measure of prevention and control of leishmaniasis. KEY WORDS Leishmaniasis, phlebotomines, São Paulo, urban parks Phlebotomines are vectors of protozoa in the genus Leishmania, the causative agents of leishmaniasis. Although infection in humans is mainly associated with rural areas, this has been changing and cases have been recorded in urban areas. Visceral leishmaniasis, for example, has been reported in large cities of Brazil, such as Campo Grande (MS), Rio de Janeiro (RJ), and Campinas (SP) (Lainson and Shaw 2005). The spread of leishmaniasis can be attributed particularly to environmental changes, such as climate change, the introduction of the protozoan into new areas, whether because of migration or tourism to endemic areas, and the adaptation of phlebotomine species to urban areas, especially because of the presence of forest fragments or green enclaves in built-up areas. However, few studies on phlebotomine fauna in the municipality of São Paulo have been published recently (Moschin et al. 2013, Castelo et al. 2015). The present study reports the results of phlebotomine collections carried out monthly between

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Leishmania infantum DNA detected in phlebotomine species from Puerto Iguazú City, Misiones province, Argentina

Cited by 21 publications

References 31 publications

Multiscale environmental determinants of Leishmania vectors in the urban-rural context

Multiscale environmental determinants of Leishmania vectors in the urban-rural context

Current status and management of canine leishmaniasis in Latin America

Occurrences of Phlebotomine Sand Flies (Diptera: Psychodidae) Potentially Associated with Leishmaniasis Transmission in Urban Parks in the City of São Paulo, Brazil

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