BackgroundAmerican tegumentary leishmaniasis is a serious Brazilian public health problem. This diseases is attributed to seven species of Leishmania, however, the majority of cases are associated with Leishmania braziliensis. Some phlebotomine species have been implicated in the transmission of this parasite, nonetheless only Psychodopygus wellcomei has had its vectorial competence demonstrated. Thus this study sought to assess some parameters related to the vectorial capacity of anthropophilic species of sand fly occurring in São Paulo state: Pintomyia fischeri, Migonemyia migonei Nyssomyia intermedia, Nyssomyia whitmani, Expapillata firmatoi and Psychodopygus ayrozai, under laboratory conditions. These parameters were the duration of the gonotrophic cycle, proportion of females which feed on hamster, the rate of infection by L. braziliensis and the duration of the extrinsic incubation period.MethodsThe sandflies were collected in three regions of the São Paulo state: Greater São Paulo and the Mogi Guaçu and Iporanga municipalities. To assess the proportion of engorged females the insects were fed on hamsters to estimate the duration of the gonotrophic cycle. To estimate the susceptibility to infection of each species, their females were fed on hamsters infected with Leishmania braziliensis and dissected to ascertain the localization of the flagellates and estimate the extrinsic incubation period.ResultsLow hamster attractiveness to Ps. ayrozai was observed. A high proportion of engorged females was observed when the hamster had its whole body exposed. The gonotrophic cycle ranged between three and eight days. Mg. migonei, Pi. fischeri, Ny. neivai, Ny. intermedia, Ny. whitmani and Ex.firmatoi presented susceptibility to infection by L. braziliensis. The highest infection rate (34.4%) was observed for Ny. whitmani and the lowest for Ny. intermedia (6.6%). Mg. migonei presented late-stage infection forms on the fifth day after feeding, but in the other species these forms were observed as from the fourth day.ConclusionsOur results, together with other parameters of their behavior under natural conditions, suggest the potential role of Ex. firmatoi as vector of this parasite and reinforce that of Mg. migonei, Pi. fischeri, Ny. neivai, Ny. intermedia and Ny. whitmani in the areas in which they occur.
A study of the phlebotomine sand flies was carried out between October 2011 and June 2013 in municipal parks in the city of São Paulo. A total of 173 specimens of 5 species were collected (Psychodopygus lloydi, Pintomyia fischeri, Lutzomyia amarali, Nyssomyia whitmani, and Migonemyia migonei). Three of these species may be involved in the transmission of the causative agent of tegumentary leishmaniasis. Surveillance and monitoring phlebotomine species from these areas are crucial as measure of prevention and control of leishmaniasis. KEY WORDS Leishmaniasis, phlebotomines, São Paulo, urban parks Phlebotomines are vectors of protozoa in the genus Leishmania, the causative agents of leishmaniasis. Although infection in humans is mainly associated with rural areas, this has been changing and cases have been recorded in urban areas. Visceral leishmaniasis, for example, has been reported in large cities of Brazil, such as Campo Grande (MS), Rio de Janeiro (RJ), and Campinas (SP) (Lainson and Shaw 2005). The spread of leishmaniasis can be attributed particularly to environmental changes, such as climate change, the introduction of the protozoan into new areas, whether because of migration or tourism to endemic areas, and the adaptation of phlebotomine species to urban areas, especially because of the presence of forest fragments or green enclaves in built-up areas. However, few studies on phlebotomine fauna in the municipality of São Paulo have been published recently (Moschin et al. 2013, Castelo et al. 2015). The present study reports the results of phlebotomine collections carried out monthly between
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