Left atrial diameter as an independent predictor of first clinical cardiovascular events in middle-aged and elderly adults: The Strong Heart Study (SHS)

Inflammation of left atrial epicardial adipose tissue is associated with paroxysmal atrial fibrillation

“…Although increased LA size is a strong risk factor for AF [28], the EAT density on CT was a significant predictor of the presence of PAF in the multiple logistic regression analysis including LA diameter in our study.…”

Left atrial size and risk of recurrent ischemic stroke in a Chinese population

“…(2008) reported that LA size, as evaluated by LA diameter/H, was a predictor of stroke, but the relation attenuated after adjustment for LV hypertrophy and LV ejection fraction. On the contrary, LA diameter was not found to be associated with stroke in two prospective studies (Gardin et al., 2001; Kizer et al., 2006). In addition, Benjamin et al.…”

“…Left atrial (LA) size increases in response to two main pathophysiologic conditions: pressure and volume overload (Leung et al., 2008). As an indicator of diastolic burden, LA enlargement is proven to be correlated with higher risk of atrial fibrillation (AF; Psaty et al., 1997; Tsang et al., 2001; Vaziri, Larson, Benjamin, & Levy, 1994), cardiovascular events (Gardin et al., 2001; Kizer et al., 2006), and all‐cause mortality (Bouzas‐Mosquera et al., 2011; Nagarajarao et al., 2008). A number of studies performed in the general population have evaluated the relationship between left atrial size and stroke, but the conclusions vary (Barnes et al., 2004; Benjamin, D'Agostino, Belanger, Wolf, & Levy, 1995; Bouzas‐Mosquera et al., 2011; Di Tullio, Sacco, Sciacca, & Homma, 1999; Gardin et al., 2001; Kizer et al., 2006; Nagarajarao et al., 2008).…”

“…As an indicator of diastolic burden, LA enlargement is proven to be correlated with higher risk of atrial fibrillation (AF; Psaty et al., 1997; Tsang et al., 2001; Vaziri, Larson, Benjamin, & Levy, 1994), cardiovascular events (Gardin et al., 2001; Kizer et al., 2006), and all‐cause mortality (Bouzas‐Mosquera et al., 2011; Nagarajarao et al., 2008). A number of studies performed in the general population have evaluated the relationship between left atrial size and stroke, but the conclusions vary (Barnes et al., 2004; Benjamin, D'Agostino, Belanger, Wolf, & Levy, 1995; Bouzas‐Mosquera et al., 2011; Di Tullio, Sacco, Sciacca, & Homma, 1999; Gardin et al., 2001; Kizer et al., 2006; Nagarajarao et al., 2008). Some authors (Barnes et al., 2004; Nagarajarao et al., 2008) supported the association between LA enlargement and stroke while others (Gardin et al., 2001; Kizer et al., 2006) oppose it, and some found that the association was influenced by gender (Benjamin et al., 1995; Bouzas‐Mosquera et al., 2011; Di Tullio et al., 1999).…”

“…A number of studies performed in the general population have evaluated the relationship between left atrial size and stroke, but the conclusions vary (Barnes et al., 2004; Benjamin, D'Agostino, Belanger, Wolf, & Levy, 1995; Bouzas‐Mosquera et al., 2011; Di Tullio, Sacco, Sciacca, & Homma, 1999; Gardin et al., 2001; Kizer et al., 2006; Nagarajarao et al., 2008). Some authors (Barnes et al., 2004; Nagarajarao et al., 2008) supported the association between LA enlargement and stroke while others (Gardin et al., 2001; Kizer et al., 2006) oppose it, and some found that the association was influenced by gender (Benjamin et al., 1995; Bouzas‐Mosquera et al., 2011; Di Tullio et al., 1999). However, the relationship between LA size and recurrent ischemic stroke was less reported.…”