Lead toxicity and potential therapeutic effect of plant-derived polyphenols

Niu, Chengu; Dong, Miaoxian; Niu, Yingcai

doi:10.1016/j.phymed.2023.154789

Cited by 9 publications

(3 citation statements)

References 129 publications

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“…Curcumin encapsulated in a pluronic block copolymer was found to have anticancer efficacy on par with free curcumin and a delayed and sustained release profile. These novel approaches can potentially improve treating many human ailments (Niu et al 2023). N-acetylcysteine (NAC) has been shown in a recent study on a group of lead-exposed employees to lower blood lead levels significantly.…”

Section: Lead Poisoning and Counteracting Measures For Reducing Expos...mentioning

confidence: 99%

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Sources, blood concentrations, and approaches for reducing exposure to lead: A critical appraisal on lead poisoning

et al. 2023

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Lead, a non-essential metal, enters the body in various ways, making it a major public health issue. Painters and smelters report lead poisoning in children and staff. Mining and battery workers risk lead exposure. Traditional and cultural remedies may include dangerous quantities of lead, producing lead poisoning. These drugs must be properly understood and regulated to avoid toxicity. Lead poisoning symptoms vary by duration and severity. Lead first impairs cognition, development, and behaviour by damaging the neural system. Time degrades reproductive and haematological systems. Lead's quiet entry into the body makes it deadly. Acute lead nephropathy damages kidneys at 100mg/dL. Lead levels exceeding 150mg/dL may induce encephalopathy. Blood lead levels indicate lead poisoning severity. Lead levels over 10g/dL in children and 40g/dL in adults are hazardous. Lead toxicity affects various organs. Lead may induce hypertension and cardiovascular disease. It may also cause chronic kidney disease and renal failure. Lead exposure may impede fertility, cause miscarriages, and alter foetal development; hence the reproductive system is vulnerable. Symptoms and lead levels may be treated with different approaches. Lead chelation treatment is frequent. Other vitamins and medications may enhance organ function and treat lead poisoning. Lead poisoning prevention requires widespread awareness. Strict standards and education regarding lead-contaminated products and conventional remedies should reduce occupational lead exposure. Regular blood lead level monitoring, especially in youngsters and lead workers, may help detect and treat lead poisoning early. Lead poisoning has serious health consequences. Understanding lead exposure pathways, identifying symptoms, and preventing lead poisoning is essential to public health and organ system protection.

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Section: Lead Poisoning and Counteracting Measures For Reducing Expos...mentioning

confidence: 99%

“…poisoning. Therefore, it is important to know where the lead came from to recognize the signs of lead poisoning in patients of varied ages and blood lead concentrations (Cantor et al 2019;Lakka et al 2023;Niu et al 2023). The data provided by case reports is invaluable.…”

Section: Introductionmentioning

confidence: 99%

Sources, blood concentrations, and approaches for reducing exposure to lead: A critical appraisal on lead poisoning

et al. 2023

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“…This was called lead sugar and was made from grape juice or wine in lead vessels. 1,2 As defined in Regulation (EC) No 1333/2008 of the European Parliament and of the Council of 16 December 2008 on food additives, 3 a food additive is any substance not normally consumed as a food in itself and not used as a characteristic ingredient of food, irrespective of its possible nutritional value, the intentional addition of which to food for technological reasons during its manufacture, processing, preparation, treatment, packaging, transport or storage results in, or may reasonably be expected to result in, that substance or its derivatives become, directly or indirectly, an ingredient of that food. 3 Food safety is one of the most important aspects of human nutrition.…”

Section: Introductionmentioning

confidence: 99%

What do parents of children know about food additives in selected foods?

Polak,

Osmala-Kurpiewska

2024

Pol. Ann. Med.

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IntroductionFood additives are used in foods by manufacturers to prevent unfavourable changes in colour, taste and smell and to extend shelf life. Consumption of highly processed products containing large amounts of food additives can lead to accumulation of these substances in the body and cause adverse health effects.AimThe aim of the study was to assess parents' knowledge of selected food additives and their impact on the health of preschool children.Material and methodsThe original survey was conducted in March 2022. In total, 112 parents of preschool children attending kindergartens in the Silesian Voivodeship were interviewed. The questionnaire consisted of information and 18 questions, including the respondents' awareness of the presence of food additives in food and their impact on human health. The survey results were prepared in Microsoft Office Excel 2019 and Statistica.Results and discussionIt was found that less than half of those surveyed (45.53%) thought that the information provided on food additives was easy to understand. More than half of those surveyed (52.68%) did not know that the consumption of products with added benzoic acid can lead to hypersensitivity reactions in patients with bronchial asthma, allergic rhinitis and skin allergies.ConclusionsThe potential health effects of consuming foods containing selected food additives were not known by most of the parents surveyed. Educational activities to increase parents' knowledge about food additives are recommended.

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