Lead Poisoning

Dhar, Siddhartha; Garg, Divyani

doi:10.1056/nejmicm2210842

Cited by 2 publications

(2 citation statements)

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“…The main effects of Pb exposure include neurological, respiratory, and cardiovascular disorders [ 85 , 86 ]. These are usually based on inflicting disturbances during immune modulation as well as oxidative and inflammatory mechanisms and are associated with a multitude of diseases [ 87 , 88 , 89 ]. Regarding the influence of Pb on cardiovascular disease, the study by Zeller et al, has to be mentioned, in which the authors were able to show that Pb is a novel and importantly independent risk factor for vascular intimal hyperplasia, a prerequisite for growing atherosclerosis [ 90 ].…”

Section: Non-essential/toxic Trace Elementsmentioning

confidence: 99%

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The Role of Trace Elements in Cardiovascular Diseases

Wechselberger,

Messner,

Bernhard

2023

Toxics

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Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. Non-essential trace elements are therefore regarded as serious environmental hazards that are harmful to health even in low concentrations. Many representatives of these elements are present as pollutants in our environment, and many people may be exposed to significant amounts of these substances over the course of their lives. Among the most common non-essential trace elements are heavy metals, which are also associated with acute poisoning in humans. When these elements accumulate in the body over years of chronic exposure, they often cause severe health damage in a variety of tissues and organs. In this review article, the role of selected essential and non-essential trace elements and their role in the development of exemplary pathophysiological processes in the cardiovascular system will be examined in more detail.

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Section: Non-essential/toxic Trace Elementsmentioning

confidence: 99%

Section: Lead (Pb)mentioning

confidence: 99%

The Role of Trace Elements in Cardiovascular Diseases

Wechselberger,

Messner,

Bernhard

2023

Toxics

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Neurotoxicology: a clinical systems-based review

Vonberg,

Blain

2024

Pract Neurol

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Neurological disease caused by toxins is widespread but under-recognised. Despite increasing public interest and a growing number of novel potential neurotoxins, diagnosis of neurotoxic disease is often delayed or missed, resulting in poorer patient outcomes. This article discusses neurotoxic syndromes using a systems-based approach, focusing on environmental and occupational agents. We do not discuss recreational drugs, pharmaceutical agents or developmental neurotoxins in detail. We aim to provide neurologists with a working understanding of the scenarios in which a clinical presentation may be due to a neurotoxin and how to approach confirmation of the diagnosis.

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Lead Poisoning

Cited by 2 publications

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The Role of Trace Elements in Cardiovascular Diseases

The Role of Trace Elements in Cardiovascular Diseases

Neurotoxicology: a clinical systems-based review

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