The Role of Trace Elements in Cardiovascular Diseases

Abstract

Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. Non-essential trace elements are therefore regarded as serious environmental hazards that are harmful to health even in low concentrations. Many representatives of these elements are present as pollutants in our environment, and many people may be exposed to significant amounts of these substances over the course of their lives. Among the most common non-essential trace elements are heavy metals, which are also associated with acute poisoning in humans. When these elements accumulate in the body over years of chronic exposure, they often cause severe health damage in a variety of tissues and organs. In this review article, the role of selected essential and non-essential trace elements and their role in the development of exemplary pathophysiological processes in the cardiovascular system will be examined in more detail.

High serum copper as a risk factor of all-cause and cause-specific mortality among US adults, NHANES 2011–2014

“…certain metallic elements in the body also contributes (5)(6)(7). Metal elements are exposed more and more frequently in our daily lives and can be ingested in a variety of ways, including air inhalation, skin contact, and ingestion of metal-contaminated food (8)(9)(10).…”