Le syndrome d’apnées obstructives du sommeil : une cause de troubles cognitifs chez les personnes âgées ?

Kinugawa, Kiyoka; Nguyen‐Michel, Vi‐Huong; Mariani, Javier

doi:10.1016/j.revmed.2014.02.005

Cited by 9 publications

(2 citation statements)

References 53 publications

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“…The cognitive deficit often observed in the elderly might also have contributed to a distorted assessment of QoL in the present study. A cognitive deficit could itself be associated with OSA 21 23 …”

Section: Discussionmentioning

confidence: 99%

Obstructive sleep apnea and quality of life in elderly patients with a pacemaker

Lima¹,

Brito

Martins

et al. 2019

J. bras. pneumol.

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Objective: To evaluate quality of life in elderly patients with obstructive sleep apnea (OSA) who have a pacemaker. Methods: This was a cross-sectional study involving elderly patients (≥ 60 years of age) with a pacemaker. The dependent variable was quality of life, as evaluated with the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). Sociodemographic and clinical parameters, including anxiety and depression (Hospital Anxiety and Depression Scale score), as well as the presence of OSA (defined as an apnea-hypopnea index ≥ 15 events/h), were analyzed as independent variables. Patients with cognitive/neurological deficits or decompensated heart failure were excluded. Results: We evaluated 72 patients, 17 (23.6%) of whom presented OSA. Of those 17 patients, 9 (52.9%) were male. The mean age was 72.3 ± 9.3 years. A diagnosis of OSA was not associated with gender (p = 0.132), age (p = 0.294), or body mass index (p = 0.790). There were no differences between the patients with OSA and those without, in terms of the SF-36 domain scores. Fourteen patients (19.4%) presented moderate or severe anxiety. Of those 14 patients, only 3 (21.4%) had OSA (p = 0.89 vs. no OSA). Twelve patients (16.6%) had moderate or severe depression. Of those 12 patients, only 2 (16.6%) had OSA (p = 0.73 vs. no OSA). Conclusions: In elderly patients with a pacemaker, OSA was not found to be associated with quality of life or with symptoms of anxiety or depression.

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Section: Discussionmentioning

confidence: 99%

Obstructive sleep apnea and quality of life in elderly patients with a pacemaker

Lima¹,

Brito

Martins

et al. 2019

J. bras. pneumol.

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“…However, as there is increasing incidence of sleep apneas and hypopneas with increasing weight and sleep breathing disorders, and these variables should be taken into the consideration. According to some reports, breathing disorders during sleep occur more often in AD than among persons without dementia (Hoch et al, 1986 ; Gehrman et al, 2003 ; Janssens et al, 2009 ; Kinugawa et al, 2014 ). In other studies, differences in the frequency of sleep breathing disorders in PSG studies in AD, in comparison to control groups, were minor (Bliwise, 2002 ; Moraes et al, 2008 ); while in some studies these differences have not been noticed at all (Bliwise et al, 1989 ).…”

Section: Introductionmentioning

confidence: 99%

Sleep Disorders Associated With Alzheimer's Disease: A Perspective

et al. 2018

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Sleep disturbances, as well as sleep-wake rhythm disturbances, are typical symptoms of Alzheimer's disease (AD) that may precede the other clinical signs of this neurodegenerative disease. Here, we describe clinical features of sleep disorders in AD and the relation between sleep disorders and both cognitive impairment and poor prognosis of the disease. There are difficulties of the diagnosis of sleep disorders based on sleep questionnaires, polysomnography or actigraphy in the AD patients. Typical disturbances of the neurophysiological sleep architecture in the course of the AD include deep sleep and paradoxical sleep deprivation. Among sleep disorders occurring in patients with AD, the most frequent disorders are sleep breathing disorders and restless legs syndrome. Sleep disorders may influence circadian fluctuations of the concentrations of amyloid-β in the interstitial brain fluid and in the cerebrovascular fluid related to the glymphatic brain system and production of the amyloid-β. There is accumulating evidence suggesting that disordered sleep contributes to cognitive decline and the development of AD pathology. In this mini-review, we highlight and discuss the association between sleep disorders and AD.

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Examining the association between obstructive sleep apnea and cardiometabolic risk factors in the elderly

Kao

Chang³

et al. 2018

Sleep Biol. Rhythms

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Le syndrome d’apnées obstructives du sommeil : une cause de troubles cognitifs chez les personnes âgées ?

Cited by 9 publications

References 53 publications

Obstructive sleep apnea and quality of life in elderly patients with a pacemaker

Obstructive sleep apnea and quality of life in elderly patients with a pacemaker

Sleep Disorders Associated With Alzheimer's Disease: A Perspective

Examining the association between obstructive sleep apnea and cardiometabolic risk factors in the elderly

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