LCST/UCST transition of acrylate copolymer with cosolvency behaviors in alcohol aqueous solutions

Molecular Mechanism of the Cosolvency Effect in Organic Solutes with Similar Structures

“…9 It also provides a new method for the development of highperformance materials. 10,11 Currently, an increasing number of cosolvency phenomena have been observed in many systems, which has attracted the widespread attention of researchers to explore its mechanism. 6,7,12−16 Some researchers suggest that the generation of the cosolvency may be caused by the similarity between solvent and solute molecules or the preferential solvation by the solvents.…”

“…In-depth research and the rational application of cosolvecny have profound implications and important significance in chemical engineering fields such as purification and crystallization. − Cosolvency can also be used for the separation of chiral compound using ionic liquids . It also provides a new method for the development of high-performance materials. , Currently, an increasing number of cosolvency phenomena have been observed in many systems, which has attracted the widespread attention of researchers to explore its mechanism. ,,− Some researchers suggest that the generation of the cosolvency may be caused by the similarity between solvent and solute molecules or the preferential solvation by the solvents. ,, Nevertheless, a considerable number of researchers have proposed that the cosolvency effect was induced by the changes in the spatial conformation of the compound molecules caused by the solvent composition changes, altering the intermolecular interactions between solute and solvent molecules. − Moreover, in our previous studies, it was found that the cosolvency phenomenon of proline system is mainly attributed to the changes in the aggregate form of the l -proline molecules when varying the solvent composition, and the diverse form of aggregates can affect the intermolecular interactions between solute and solvent molecules with the changes in solution composition. − Although some scholars have conducted research on the solubility difference of solutes in binary mixed solvents with similar structure and it has been found that the molecular structure of solvents has a significant impact on the solubility performance of solutes, the general mechanism of cosolvency has not been completely revealed and understood.…”