Layer-by-layer preparation of polyelectrolyte multilayer nanocapsules via crystallized miniemulsions

Abstract

Using crystallized miniemulsion nanoparticles (NPs) as synthetic templates leads to well-defined layer-by-layer (LBL) polymeric nanocapsules (NCs) under mild conditions

A comprehensive review of the structures and properties of ionic polymeric materials

“…168,204 Besides, a layer-by-layer method was often used to precisely design biomedical scaffolds from polyampholytes and ionic hydrogels for potential applications as cell culture devices, and also as nanocarriers and biosensors. [205][206][207] Future challenges for many ionic polymer materials in the biomedical fields will be deeper investigation of responsive properties in an in vivo environment. 168,204 The development of ionic polymeric materials also led to numerous water-treatment applications by designing membranes, leveraging electrostatic interactions to remove heavy metals, nanoparticles or even amino acids.…”

Self-sustaining enzyme nanocapsules perform on-site chemical reactions

“…Typically, miniemulsions can be prepared by ultrasonication as a result of cavitationinduced droplet disruption. [32][33][34] However, the high energy of the ultrasound waves and the long duration of their application are detrimental to sensitive biological molecules. The complex three-dimensional structure of the enzyme was disrupted by the use of ultrasound, resulting in a complete loss of enzymatic activity (Fig.…”

Well-Defined Diblock Poly(ethylene glycol)-b-Poly(ε-caprolactone)-Based Polymer-Drug Conjugate Micelles for pH-Responsive Delivery of Doxorubicin

“…Figure 5 illustrates the volume-average size distribution of the micelles, indicating a volume-average hydrodynamic diameter (D h,v ) of 128 ± 2 nm and a polydispersity of 0.23 for the PDC micelles. The nanostructure of the PDC micelles was characterized using transmission electron microscopy (TEM) according to our previously published sample preparation method [34]. The micelles showed high image contrast without applying any staining agent during TEM sample preparation ( Figure 6).…”