Layer by Layer Mesoporous Silica-Hyaluronic Acid-Cyclodextrin Bifunctional “Lamination”: Study of the Application of Fluorescent Probe and Host–Guest Interactions in the Drug Delivery Field

Nie, Kun; An, Qi; Zink, Jeffrey I.; Yu, Xingwen; Zhang, Yihe

doi:10.3390/ma11091745

Cited by 3 publications

(2 citation statements)

References 47 publications

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“…HA-CD gel was prepared according to literature [48]. In a 100 mL Erlenmeyer flask, 0.3 g of sodium hyaluronate and 50 mL of morpholinoethanesulfonic buffer (MES) were added and rapid stirred for 6 h. Subsequently, 0.285 g of NHS and 0.342 g of EDC were added into the Erlenmeyer flask.…”

Section: Methodsmentioning

confidence: 99%

Versatile Layer-By-Layer Highly Stable Multilayer Films: Study of the Loading and Release of FITC-Labeled Short Peptide in the Drug Delivery Field

Nie

Kumar

et al. 2019

Materials

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A viable short FITC-peptide immobilization is the most essential step in the fabrication of multilayer films based on FITC-peptide. These functional multilayer films have potential applications in drug delivery, medical therapy, and so forth. These FITC-peptides films needed to be handled with a lot of care and precision due to their sensitive nature. In this study, a general immobilization method is reported for the purpose of stabilizing various kinds of peptides at the interfacial regions. Utilizing Mesoporous silica nanoparticles can help in the preservation of these FITC-peptides by embedding themselves into these covalently cross-linked multilayers. This basic outlook of the multilayer films is potent enough and could be reused as a positive substrate. The spatio-temporal retention property of peptides can be modulated by varying the number of capping layers. The release speed of guest molecules such as tyrosine within FITC-peptide or/and adamantane (Ad)-in short peptides could also be fine-tuned by the specific arrangements of the multilayers of mesoporous silica nanoparticles (MSNs) and hyaluronic acid- cyclodextrin (HA-CD) multilayer films.

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Section: Methodsmentioning

confidence: 99%

Versatile Layer-By-Layer Highly Stable Multilayer Films: Study of the Loading and Release of FITC-Labeled Short Peptide in the Drug Delivery Field

Nie

Kumar

et al. 2019

Materials

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“…Researchers have employed LBL self-assembly for the fabrication of mesoporous silica nanoparticles and HYH–cyclodextrin films, which were constructed to load the fluorescent dyes and peptides. The release rates of these molecules were varied by the variation in the number of layers in the multilayer films [ 117 , 118 ].…”

Section: Hyh–bioceramic and Hyh–bioglass Compositesmentioning

confidence: 99%

Hyaluronic-Acid-Based Organic-Inorganic Composites for Biomedical Applications

2021

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Applications of natural hyaluronic acid (HYH) for the fabrication of organic–inorganic composites for biomedical applications are described. Such composites combine unique functional properties of HYH with functional properties of hydroxyapatite, various bioceramics, bioglass, biocements, metal nanoparticles, and quantum dots. Functional properties of advanced composite gels, scaffold materials, cements, particles, films, and coatings are described. Benefiting from the synergy of properties of HYH and inorganic components, advanced composites provide a platform for the development of new drug delivery materials. Many advanced properties of composites are attributed to the ability of HYH to promote biomineralization. Properties of HYH are a key factor for the development of colloidal and electrochemical methods for the fabrication of films and protective coatings for surface modification of biomedical implants and the development of advanced biosensors. Overcoming limitations of traditional materials, HYH is used as a biocompatible capping, dispersing, and structure-directing agent for the synthesis of functional inorganic materials and composites. Gel-forming properties of HYH enable a facile and straightforward approach to the fabrication of antimicrobial materials in different forms. Of particular interest are applications of HYH for the fabrication of biosensors. This review summarizes manufacturing strategies and mechanisms and outlines future trends in the development of functional biocomposites.

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Host-guest drug delivery by β-cyclodextrin assisted polysaccharide vehicles: A review

Sahu

Patra

Swain

2023

International Journal of Biological Macromolecules

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Layer by Layer Mesoporous Silica-Hyaluronic Acid-Cyclodextrin Bifunctional “Lamination”: Study of the Application of Fluorescent Probe and Host–Guest Interactions in the Drug Delivery Field

Cited by 3 publications

References 47 publications

Versatile Layer-By-Layer Highly Stable Multilayer Films: Study of the Loading and Release of FITC-Labeled Short Peptide in the Drug Delivery Field

Versatile Layer-By-Layer Highly Stable Multilayer Films: Study of the Loading and Release of FITC-Labeled Short Peptide in the Drug Delivery Field

Hyaluronic-Acid-Based Organic-Inorganic Composites for Biomedical Applications

Host-guest drug delivery by β-cyclodextrin assisted polysaccharide vehicles: A review

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