Host-guest drug delivery by β-cyclodextrin assisted polysaccharide vehicles: A review

Sahu, Krishna Manjari; Patra, Swapnita; Swain, Sarat K.

doi:10.1016/j.ijbiomac.2023.124338

Cited by 24 publications

(14 citation statements)

References 173 publications

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“…The major guest molecules compatible with b-CD include adamantane, azobenzene, ferrocene, and cholesterol. 44,45 CDbased host-guest supramolecular hydrogels are increasingly employed in biomedical and other fields due to the strong attraction provided by the dynamic reversibility of host-guest interactions. 18,46 In the next sections, an introduction to CDbased supramolecular hydrogels based on host-guest interactions will be provided.…”

Section: Host-guest Interactionsmentioning

confidence: 99%

Engineered cyclodextrin-based supramolecular hydrogels for biomedical applications

Zhao,

Zheng,

et al. 2024

J. Mater. Chem. B

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Section: Host-guest Interactionsmentioning

confidence: 99%

Engineered cyclodextrin-based supramolecular hydrogels for biomedical applications

Zhao,

Zheng,

et al. 2024

J. Mater. Chem. B

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“…22 The adsorption potential of β-CD is significant due to the interaction between host and guest molecules in supramolecular chemistry and the synergistic effect. 13,23 Furthermore, by incorporating the magnetic characteristics of iron oxide, β-CD can create adsorbents that can be effortlessly extracted from a water-based solution by applying an external magnetic force. 24 The cooperative agents generate a complex of β-CD with iron oxide nanomagnet components that act as the magnetic carrier.…”

Section: Introductionmentioning

confidence: 99%

“…These molecules have a unique shape that resembles cones . They have a central opening that is polar and surrounded by primary hydroxyl groups on the outer surface . The inner surface contains secondary hydroxyl groups.…”

Section: Introductionmentioning

confidence: 99%

“…It is imperative to explore the environmentally conscious properties of nanomaterials, such as their ability to combat harmful microorganisms and eliminate dyes from the surroundings . The adsorption potential of β-CD is significant due to the interaction between host and guest molecules in supramolecular chemistry and the synergistic effect. , …”

Section: Introductionmentioning

confidence: 99%

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Green Synthesis of Magnetic Supramolecules β-Cyclodextrin/Iron Oxide Nanoparticles for Photocatalytic and Antibacterial Applications

Almutairi,

Al-Rasheed,

Alaqil

et al. 2023

ACS Omega

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Iron oxide nanoparticles (Fe 3 O 4 NPs) are a fascinating field of study due to their wide range of practical applications in environmental and medical contexts. This study presents a straightforward, environmentally friendly method for producing Fe 3 O 4 NPs utilizing β-cyclodextrin (β-CD) as a reducing and capping agent. This approach results in the rapid and effective eco-friendly synthesis of β-CD/Fe 3 O 4 NPs. The properties and characteristics of β-CD/Fe 3 O 4 NPs were investigated using various methods, including ultraviolet−visible (UV/vis) spectroscopy, Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), thermogravimetry analysis (TGA), and vibrating-sample magnetometry (VSM). The absorption of β-CD/Fe 3 O 4 NPs caused a distinct peak at 349 nm, as evidenced by the results of UV/vis studies. This peak was attributed to the absorption of surface plasmon resonance. The crystalline nature of β-CD/Fe 3 O 4 NPs was confirmed through XRD analysis. The SEM and TEM analyses have verified the geometry and structural characteristics of β-CD/Fe 3 O 4 NPs. The β-CD/Fe 3 O 4 NPs exhibited remarkable effectiveness in the decomposing efficiency (%) of methylene blue (MB) dye with 52.2, 94.1, and 100% for 0.2, 0.4, and 0.6 g β-CD/ Fe 3 O 4 NPs, respectively. In addition, the highest efficiency in hunting radicals was observed (347.2 ± 8.2 mg/g) at 100 mg/mL β-CD/Fe 3 O 4 NPs; the combination of β-CD/Fe 3 O 4 NPs exhibited remarkable effectiveness in inhibiting the growth of some bacteria that cause infections. The capabilities of β-CD/Fe 3 O 4 NPs for various applications showed that these materials could be used in photocatalytic, antioxidants, and antibacterial. Additionally, the eco-friendly synthesis of these materials makes them a promising option for the remediation of harmful pollutants and microbes.

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“…[10,11] Among the macrocycles, cyclodextrins (CDs) are undoubtedly the most extensively used in biomedical and pharmaceutical applications. [12][13][14] More than 40 formulations containing native or modified CDs are currently marketed for diverse therapeutic purposes. [15] Significant progress has currently been achieved in the design of CD-based nanomedicines, as well as in supramolecular theranostics based on CD ICs.…”

Section: Introductionmentioning

confidence: 99%

Inclusion and Non‐Inclusion Complexes between Curcumin and β‐Cyclodextrin with High‐Curcumin Loading and Enhanced Aqueous Solubility Obtained by Mechanochemistry

Cabrera‐Quiñones,

López‐Méndez,

Guadarrama

2023

ChemistrySelect

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In this study, we employ mechanochemistry as an innovative strategy, using a Planetary Mill, to obtain supramolecular structures in the solid state between Curcumin (Cur) and β‐cyclodextrin (βCD), exploring different parameters such as jars and balls material (stainless steel versus zirconium oxide), milling time, as well as the effect on imposing different Cur:βCD molar ratios. Our findings demonstrate that regardless of the milling material used, the same supramolecular interactions between Cur and βCD seem to be promoted. However, depending on the molar ratio, different supramolecular modes are produced resulting in inclusion complexes (ICs) or non‐inclusion complexes (non‐ICs) by a partial or total amorphization of both Cur and βCD. Independently of the type of supramolecular complex obtained (ICs/or non‐ICs), high content of Cur was quantified in all the systems, achieving a Cur content of up to 342 mg per mmol of βCD, along with an enhancement in Cur aqueous solubility. The Cur:βCD 1 : 2 complex showed the highest aqueous solubility (around 10‐times more soluble than milled Cur). In our conditions, the optimum time to form the supramolecular complexes was 60 min. The stability of the complexes was directly related to the extent of encapsulation of Cur inside the βCD cavity.

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Host-guest drug delivery by β-cyclodextrin assisted polysaccharide vehicles: A review

Cited by 24 publications

References 173 publications

Engineered cyclodextrin-based supramolecular hydrogels for biomedical applications

Engineered cyclodextrin-based supramolecular hydrogels for biomedical applications

Green Synthesis of Magnetic Supramolecules β-Cyclodextrin/Iron Oxide Nanoparticles for Photocatalytic and Antibacterial Applications

Inclusion and Non‐Inclusion Complexes between Curcumin and β‐Cyclodextrin with High‐Curcumin Loading and Enhanced Aqueous Solubility Obtained by Mechanochemistry

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