Laparoscopic and robot-assisted procedures in patients with gastrointestinal stromal tumors (GIST) of stomach

Черноусов, А. Ф.; Ветшев, Ф П; Vychuzhanin, D.; Хоробрых, Т В; Егоров, А. В.; Zamay, Sergey S.; Gelmutdinova, E R

doi:10.17116/hirurgia20200115

Cited by 2 publications

(1 citation statement)

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“…Gastrointestinal stromal tumor (GIST) is a tumor of the mesenchymal tissue of the gastrointestinal tract with a high incidence of about 0.1–0.2 per 10,000 people [ 10 ]. The disease may be asymptomatic, and potential symptoms include abdominal pain, distension, vomiting blood, black stools, and abdominal masses [ 11 ]; however, the absence of specific symptoms and the insidiousness of the lesion complicate the effective diagnosis of the disease in the early stage [ 12 ]. The deficiency in the treatment efficiency of GIST is attributable to the small size and special location of tumors despite laparoscopic surgery as the choice of treatment with curable intent [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Endoscopy-Assisted Laparoscopic versus Laparoscopic Surgery for Gastrointestinal Stromal Tumor and the Impact on Patients’ Coagulation, Surgical Condition, and Complications

Liu

Dai²

2022

Journal of Oncology

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Objective. To assess the clinical efficiency of endoscopy-assisted laparoscopic versus laparoscopic surgery for gastrointestinal stromal tumors and the impact on patients’ coagulation, surgical condition, and complications. Methods. Between November 2016 and May 2020, 126 eligible patients diagnosed with gastrointestinal stromal tumor (GIST) in our institution were recruited. They were concurrently randomly assigned at a ratio of 1 : 1 to receive either laparoscopic gastrectomy (reference group) or endoscopy-assisted laparoscopic gastrectomy (research group). The two groups were compared in terms of patients’ coagulation function, surgical conditions, and complications. Results. The two groups had similar preoperative coagulation indices and the postoperative levels of activated partial thromboplastin time (APTT) and thromboplastin time (TT) ( P > 0.05 ). Compared with the reference group, the research group showed lower PT levels (10.48 ± 0.68 vs. 11.97 ± 0.46) and higher FIB levels (0.67 ± 0.11 vs. 0.29 ± 0.07) ( P < 0.05 ). Compared with the reference group, the study group had shorter operative time (81.21 ± 10.24 min versus 98.98 ± 15.31 min), shorter surgical incision (3.63 ± 1.12 cm versus 5.01 ± 1.14 cm), and less intraoperative bleeding (18.74 ± 6.98 ml versus 58.69 ± 15.87 ml) ( P < 0.05 ). A markedly shorter length of hospital stay, time to the first postoperative exhaustion, and duration of drainage tube and gastric tube dwelling were observed in the research group versus the reference group ( P < 0.05 ). The study group presented higher nutritional levels of patients at 3 days after surgery and a lower incidence of complication. Conclusion. Endoscopy-assisted laparoscopic treatment shows significant improvements in the efficiency of minimally invasive surgery and ensures a better prognosis and quality of life of patients with a good safety profile, so it is worthy of clinical application.

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Section: Discussionmentioning

confidence: 99%