Landscape of dietary factors associated with risk of gastric cancer: A systematic review and dose-response meta-analysis of prospective cohort studies

Fang, Xuexian; Wei, Jiayu; He, Xuyan; An, Peng; Wang, Hao; Jiang, Li; Shao, Dandan; Liang, Han; Li, Yang; Wang, Fudi; Min, Junxia

doi:10.1016/j.ejca.2015.09.010

Cited by 194 publications

(155 citation statements)

References 37 publications

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“…However, studies demonstrated an effect of fruits and vegetables on the risk of cancer, and many of the tested extracts have genotoxic potential [67,68]. Ribeiro et al .…”

Section: Discussionmentioning

confidence: 99%

Euterpe oleracea Extract (Açaí) Is a Promising Novel Pharmacological Therapeutic Treatment for Experimental Endometriosis

et al. 2016

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This study investigated the therapeutic potential of Euterpe oleracea extract (açaí) on the growth and survival of endometriotic lesions using an experimental model. Twenty female Sprague-Dawley rats were randomized into two groups after the implantation and establishment of autologous endometrium onto the peritoneum abdominal wall and treated with 200 mg/kg hydroalcoholic solution extract from açaí stone or vehicle via gastric tube for 30 consecutive days. Body weight, lesion surface areas, histological and immunohistochemistry analyses of vascular endothelial growth factor (VEGF), VEGF receptor-2 (VEGFR-2), metalloproteinase-9 (MMP-9), cyclooxygenase-2 (COX-2) and F4-80 were performed. Levels of VEGF, VEGFR-2, MMP-9 and COX-2 mRNA were measured. Flow cytometry of F4-80 was performed, and ELISA immunoassays measured prostaglandin E2 (PGE2), VEGF and nitric oxide (NO) and concentrations. Macrophage cell line J774.G8 was treated with 10, 20, and 40 μg/mL of açaí for 24, 48 and 72 h, and cell viability was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays. Açaí treatment significantly decreased the implant size, and histological examination indicated atrophy and regression. A reduction in immunostaining and mRNA expression of VEGF, MMP-9 and COX-2 was observed, and F4-80 was lower in the treated group than the control group. The treated group also exhibited lower concentrations of PGE2, VEGF and NO compared to the control group. Macrophages cells treated with 20 and 40 μg/ml of açaí reduced cell viability in about 50% after 24, 48 and 72 h. Our results suggest that açaí effectively suppressed the establishment and growth of endometriotic lesions, and this agent is a promising novel pharmacological therapeutic treatment for endometriosis.

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“…However, studies demonstrated an effect of fruits and vegetables on the risk of cancer, and many of the tested extracts have genotoxic potential [67,68]. Ribeiro et al .…”

Section: Discussionmentioning

confidence: 99%

Euterpe oleracea Extract (Açaí) Is a Promising Novel Pharmacological Therapeutic Treatment for Experimental Endometriosis

et al. 2016

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“…Los alimentos que deberían incorporarse a esta regulación, según los nutricionistas y estudiantes son el alcohol y la comida chatarra, dado el alto consumo de estos productos en la población. 25,26 . En cuanto a la comida chatarra, son tipos de alimentos asociados a factores de riesgo como presión arterial elevada, altos niveles de glucosa en sangre, colesterol alto y dieta baja en frutas y verduras, que, a su vez, se asocian a elevadas tasas de mortalidad a nivel mundial 27 .…”

Section: Discussionunclassified

Ley de alimentos: una mirada de los nutricionistas y estudiantes de nutrición y dietética de Chile

Durán-Agüero¹,

Parra²,

Ahumada³

et al. 2017

Rev Esp Nutr Hum Diet

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[ahead of print]Freely available online -OPEN ACCESS La Revista Española de Nutrición Humana y Dietética se esfuerza por mantener a un sistema de publicación continua, de modo que los artículos se publican antes de su formato final (antes de que el número al que pertenecen se haya cerrado y/o publicado). De este modo, intentamos poner los artículos a disposición de los lectores/usuarios lo antes posible.The Spanish Journal of Human Nutrition and Dietetics strives to maintain a continuous publication system, so that the articles are published before its final format (before the number to which they belong is closed and/or published). In this way, we try to put the articles available to readers/users as soon as possible. y un 99,2% de los estudiantes NyD declararon conocer la ley; un 81,7% de los nutricionistas y un 85,0% de los estudiantes indicaron estar de acuerdo con la ley de alimentos. Al consultar sobre la efectividad de la aplicación de la ley en los colegios, un 49% de los nutricionistas y un 51,5% de los estudiantes la consideraron efectiva, a pesar de que no impide la venta de alimentos no saludables en el exterior de los colegios. El 88,2% de los nutricionistas y un 86,2% de los estudiantes NyD señalaron que realizó educación respecto a la ley de alimentos a pacientes. Revista Española de NutriciónConclusión: Los nutricionistas y estudiantes de NyD en Chile tienen un buen conocimiento de la ley, una percepción favorable de ella y han educado a sus usuarios sobre ella. Sin embargo, consideran relevante mejorar la aplicación de la ley al interior de los establecimientos educacionales e implementar modificaciones futuras que incluyan aspectos como la restricción de venta de alimentos con sellos y así limitar su consumo en población infantil.Palabras clave: Legislación sobre Alimentos; Nutricionistas; Valor Nutritivo; Etiquetado de Alimentos; Publicidad como Asunto.

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“…Therefore, risk factors for gastric cancer and its association with GT or GTE have been investigated in six cohort studies from Japan [242][243][244][245][246][247], but no similar cohort study was published from other countries ( Table 9). A variety of factors have been used to explain areas of high incidence, among them dietary nitrite and nitrosamines [248] or high salt food [249] as food specific carcinogens, and gastric inflammation in H. pylori infection [250]. As protective factors, fruit and vitamin C intake has been published [249].…”

Section: Gastric Cancermentioning

confidence: 99%

“…A variety of factors have been used to explain areas of high incidence, among them dietary nitrite and nitrosamines [248] or high salt food [249] as food specific carcinogens, and gastric inflammation in H. pylori infection [250]. As protective factors, fruit and vitamin C intake has been published [249].…”

Section: Gastric Cancermentioning

confidence: 99%

Green Tea and Its Extracts in Cancer Prevention and Treatment

et al. 2017

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Green tea (GT) and green tea extracts (GTE) have been postulated to decrease cancer incidence. In vitro results indicate a possible effect; however, epidemiological data do not support cancer chemoprevention. We have performed a PubMED literature search for green tea consumption and the correlation to the common tumor types lung, colorectal, breast, prostate, esophageal and gastric cancer, with cohorts from both Western and Asian countries. We additionally included selected mechanistical studies for a possible mode of action. The comparability between studies was limited due to major differences in study outlines; a meta analysis was thus not possible and studies were evaluated individually. Only for breast cancer could a possible small protective effect be seen in Asian and Western cohorts, whereas for esophagus and stomach cancer, green tea increased the cancer incidence, possibly due to heat stress. No effect was found for colonic/colorectal and prostatic cancer in any country, for lung cancer Chinese studies found a protective effect, but not studies from outside China. Epidemiological studies thus do not support a cancer protective effect. GT as an indicator of as yet undefined parameters in lifestyle, environment and/or ethnicity may explain some of the observed differences between China and other countries.

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Landscape of dietary factors associated with risk of gastric cancer: A systematic review and dose-response meta-analysis of prospective cohort studies

Cited by 194 publications

References 37 publications

Euterpe oleracea Extract (Açaí) Is a Promising Novel Pharmacological Therapeutic Treatment for Experimental Endometriosis

Euterpe oleracea Extract (Açaí) Is a Promising Novel Pharmacological Therapeutic Treatment for Experimental Endometriosis

Ley de alimentos: una mirada de los nutricionistas y estudiantes de nutrición y dietética de Chile

Green Tea and Its Extracts in Cancer Prevention and Treatment

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