Lactones from Angiopteris caudatiformis

Abstract

Angiopterlactones A (1) and B (2), two unique lactones, and three known lactones, osmundalactone (3), osmundalin (4), and 3,5-dihydroxy-gamma-caprolactone (5), have been isolated from the rhizome of Angiopteris caudatiformis. The structures of 1 and 2 were determined by NMR and MS methods, and the structure of 2 was confirmed by X-ray crystallography. The absolute configurations of 1 and 2 were assigned by application of the CD excitation chirality method and the modified Mosher's method. Compound 1 was slightly cytotoxic against HeLa cells, with an IC(50) value of 68.8 microM, and compounds 3 and 4 showed moderate insect antifeeding activity against Plutella xylostella and Heliothis virescens.

(±)-Pestalachloride D, an Antibacterial Racemate of Chlorinated Benzophenone Derivative from a Soft Coral-Derived Fungus Pestalotiopsis sp.

“…The zebrafish embryo teratogenicity assays were evaluated according to the described methods [4,5]. The agrochemical assays were evaluated by the methods described previously [15]. …”

Comparative Evaluation of the Chemical Composition, Antioxidant and Antimicrobial Activities of the Volatile Oils of Hawk Tea from Six Botanical Origins

“…reported that the most abundant compounds in the LPH volatile oil were 1,8‐cineole, carvone and limonene. Yu et al . also found that, the ACH volatile oil was characterized by the dominant presence of isocaryophyllene and germacrene B.…”

Formal Synthesis of Angiopterlactone B via Enantioselective Reduction of Ketone with Daucus Carota Root

“…Angiopterlactones are diverse class of lactones integrated with ether linkage, which was isolated as metabolites from the plant Angiopteris caudatiformis by Zou and co‐workers in 2009 and projected structures of angiopterlactone A 1 , angiopterlactone B 2 , along with osmundalctone 4, osmundalin 3 and 3–5 dihydroxy γ‐caprolactone 5 . Authors did not demonstrated stereochemistry of lactone 3 , 4 and 5 in isolation paper . Among all these compounds only angiopterlactone A exhibits cytotoxic activity against HeLa cells, while osmundalactone and osmundalin shows insecticidal activity .…”

“…Authors did not demonstrated stereochemistry of lactone 3 , 4 and 5 in isolation paper . Among all these compounds only angiopterlactone A exhibits cytotoxic activity against HeLa cells, while osmundalactone and osmundalin shows insecticidal activity . Indistinguishable lactone 1‐(5‐oxotetrahydrofuran‐2yl) ethyl 2‐phenyl acetate 6 was isolated from fungus Nigrospora sphaerica in 2009 by Pei and et al .…”