Laboratory models to evaluate phytotoxicity of sulphadimethoxine on terrestrial plants

Migliore, Luciana; Civitareale, Cinzia; Cozzolino, Salvatore; Casoria, Paolo; Brambilla, G; Gaudio, Luciano

doi:10.1016/s0045-6535(98)00336-1

Cited by 69 publications

(28 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The acute toxicity of Flumequine on L. salicaria plants clearly agrees with our previous experimental data on the toxicity of Sulphadimethoxine on crop plants (Hordeum disticum L., Panicum miliaceum L., Pisum sativum L. and Zea mays L.) and weeds (Amaranthus retro¯exus L., Plantago major L. and Rumex acetosella L.) (Migliore et al, 1995a(Migliore et al, , 1996b(Migliore et al, , 1997b(Migliore et al, , 1998Brambilla et al, 1996); it further demonstrates the a nity of antibacterial drugs for the biota and con®rms the methodological validity of our ecotoxicological tool, skill with di erent species and di erent drugs.…”

Section: Discussionsupporting

confidence: 90%

“…They were sterilised and transferred to Petri dishes for germination at 25°C in the dark. According to the already used method (Migliore et al, 1995a(Migliore et al, , 1996b(Migliore et al, , 1997b(Migliore et al, , 1998 after germination, seedlings were transferred to multipurpose jars on sterile solid Murashige and Skoog medium (Sigma, Milan, Italy), with or without Flumequine (Sigma, Milan, Italy) (nominal concentrations). The drug, completely soluble in alkaline medium, as happens in run-o water from intensive ®sh farming, was dissolved in NaOH 5N, ®l-tered through a sterile Millipore 0.45 lm ®lter and added to the medium at 45°C; each control contained the same NaOH concentration of the referent treated jar.…”

Section: Methodsmentioning

confidence: 99%

“…Induction of resistance in the microbial community in the area close to a farm facility was determined (Migliore et al, 1996a). Plants are able to absorb and accumulate antibiotics under laboratory conditions: in those tests both crop plants and weeds demonstrated antimicrobial drug phytotoxicity and bioaccumulation (Migliore et al, 1995a(Migliore et al, , 1996b(Migliore et al, , 1997b(Migliore et al, , 1998.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Phytotoxicity to and uptake of flumequine used in intensive aquaculture on the aquatic weed, Lythrum salicaria L.

2000

View full text Add to dashboard Cite

Phytotoxicity of Flumequine on the aquatic weed Lythrum salicaria L. was determined by two laboratory models: a single concentration test, by which the e ects of 100 mg l À1 were evaluated after 10, 20, 30 days and a multiple concentration test, by which the e ects of 5000±1000±500±100±50 lg l À1 were evaluated after 35-day exposure. 100 mg l À1 are highly toxic and signi®cantly decrease the growth of plants; this e ect increases with time. Concentrations between 5000 and 50 lg l À1 induced hormesis in plants, by signi®cantly increasing mean number and dimension of leaves and secondary roots. The e ect is the highest at 50 lg l À1 and decreases with increase in concentration. Both toxic e ect and hormesis can be related to plant drug uptake, quite high, in the order of lg g À1 . The ecological implication of Flumequine contamination in aquatic environments and the possible use of Lythrum salicaria for bioremediation and/ or monitoring technique are discussed. Ó

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Phytotoxicity to and uptake of flumequine used in intensive aquaculture on the aquatic weed, Lythrum salicaria L.

2000

View full text Add to dashboard Cite

show abstract

“…Antibiotics used in livestock production are excreted in the urine and faeces of animals and often appear in manure. From here they can cause some problems in terres-trial ecosystems such as adverse effects on nitrifying bacteria [11] or growth inhibition of crop plants and weeds by bioaccu-mulation [129]. The presence of antibiotics in STP influents may also impair treatment processes that use bacteria and cause toxic effects in the downstream aquatic and/or terrestrial ecosystems at different trophic levels [11].…”

Section: Antibioticsmentioning

confidence: 99%

Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment

Santos

Araújo

Fachini

et al. 2010

Journal of Hazardous Materials

1,287

533

View full text Add to dashboard Cite

Pharmaceuticals are biologically active and persistent substances which have been recognized as a con-tinuing threat to environmental stability. Chronic ecotoxicity data as well as information on the current distribution levels in different environmental compartments continue to be sparse and are focused on those therapeutic classes that are more frequently prescribed and consumed. Nevertheless, they indicate the negative impact that these chemical contaminants may have on living organisms, ecosystems and ultimately, public health. This article reviews the different contamination sources as well as fate and both acute and chronic effects on nontarget organisms. An extensive review of existing data in the form of tables, encompassing many therapeutic classes is presented.Keywords: Pharmaceuticals, Sources, Environmental fate, Ecotoxicological effects

show abstract

“…Hence, there is a potential risk that plants might transfer antibiotics from the soil into the food chain. There are some reports dealing with the effects of antibiotics on plant growth and development (Batchelder, 1981(Batchelder, , 1982Migliore et al, 1998;Bradel et al, 2000;Jjemba, 2002a,b), but information is scant on characterizing the antibiotic uptake into higher plants.…”

Section: Introductionmentioning

confidence: 99%

Uptake of oxytetracycline and its phytotoxicity to alfalfa (Medicago sativa L.)

Kong

Zhu

Liang

et al. 2007

Environmental Pollution

189

View full text Add to dashboard Cite

Plant uptake of antibiotic oxytetracycline is energy-dependent. AbstractA series of experiments were conducted in a hydroponic system to investigate the uptake of oxytetracycline (OTC) and its toxicity to alfalfa (Medicago sativa L.). OTC inhibited alfalfa shoot and root growth by up to 61% and 85%, respectively. The kinetics of OTC uptake could be well described by MichaeliseMenten equation with V max of 2.25 mmol g À1 fresh weight h À1 , and K m of 0.036 mM. The uptake of OTC by alfalfa was strongly inhibited by the metabolic inhibitor, 2,4-DNP (2,4-dinitrophenol), at pH 3.5 and 6.0, but not by the aquaporin competitors, glycerol and Ag þ . OTC uptake, however, was significantly inhibited by Hg 2þ , suggesting that the inhibition of influx was due to general cellular stress rather than the specific action of Hg 2þ on aquaporins. Results from the present study suggested that OTC uptake into alfalfa is an energy-dependent process.

show abstract

Laboratory models to evaluate phytotoxicity of sulphadimethoxine on terrestrial plants

Cited by 69 publications

References 8 publications

Phytotoxicity to and uptake of flumequine used in intensive aquaculture on the aquatic weed, Lythrum salicaria L.

Phytotoxicity to and uptake of flumequine used in intensive aquaculture on the aquatic weed, Lythrum salicaria L.

Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment

Uptake of oxytetracycline and its phytotoxicity to alfalfa (Medicago sativa L.)

Contact Info

Product

Resources

About