Lab-on-PCB: Low Cost 3D Microelectrode Array Device for Extracellular Recordings

Cabello, Miguel; Aracil, Carmen; Perdigones, Francisco; Quero, J.M.; Rocha, Paulo R. F.

doi:10.1109/cde.2018.8596774

Cited by 1 publication

(1 citation statement)

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“…There are several examples of MEAS manufactured with this technology: a flexible one, using polyimide as both substrate and insulation material [16], and a fabricated one, using PCB (Eco MEA) with Elpemer®2467 or PSR-4000 GP01EU (Peters, Kempen, Germany and Taiyo America, Carson City, NV, USA, respectively) [17] as insulation material. Other designs can be found in state of the art such as the PCB-based 3D MEA described on [18]. This MEA has gold electrodes covered with SU-8 as an insulation layer.…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility Study of a Commercial Printed Circuit Board for Biomedical Applications: Lab-on-PCB for Organotypic Retina Cultures

et al. 2021

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Printed circuit board (PCB) technology is well known, reliable, and low-cost, and its application to biomedicine, which implies the integration of microfluidics and electronics, has led to Lab-on-PCB. However, the biocompatibility of the involved materials has to be examined if they are in contact with biological elements. In this paper, the solder mask (PSR-2000 CD02G/CA-25 CD01, Taiyo Ink (Suzhou) Co., Ltd., Suzhou, China) of a commercial PCB has been studied for retinal cultures. For this purpose, retinal explants have been cultured over this substrate, both on open and closed systems, with successful results. Cell viability data shows that the solder mask has no cytotoxic effect on the culture allowing the application of PCB as the substrate of customized microelectrode arrays (MEAs). Finally, a comparative study of the biocompatibility of the 3D printer Uniz zSG amber resin has also been carried out.

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Section: Introductionmentioning

confidence: 99%