La neurosyphilis : une cause rare de démence

Mahmoudi, Rachid; Maheut-Bosser, A.; Hanesse, B.; Paille, F.

doi:10.1016/j.revmed.2006.07.014

Cited by 7 publications

(2 citation statements)

References 4 publications

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“…For instance, Fujimoto et al [6] reported a case who presented with immediate, recent and remote memory disturbances. This was consistent with previously reported cases [7,8,9,10,11]. Unfortunately, these studies lacked systematic neuropsychological examinations, and they did not include other dementia patient groups (e.g.…”

Section: Introductionsupporting

confidence: 91%

Cognitive Impairment in Mild General Paresis of the Insane: AD-Like Pattern

Wang¹,

Guo²,

Zhou

et al. 2011

Dement Geriatr Cogn Disord

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Background/Aims: We investigated the clinical and cognitive features of patients with mild general paresis of the insane (GPI) in comparison to Alzheimer’s disease (AD) patients, mild frontotemporal dementia (FTD) patients and normal elderly individuals. Methods: Twelve patients with mild GPI, 24 patients with mild AD, 11 patients with mild FTD and 36 healthy subjects participated in the current study. A comprehensive neuropsychological battery was used to assess memory, language, attention, executive function, visuospatial ability, etc. In addition, cranial MRI were also obtained from the 3 patient groups. Results: Mild GPI showed a similar pattern of cognitive impairments in memory, language and executive function to mild AD, but a mixed pattern of dissimilarities to mild FTD. Mild GPI patients had more complaints and positive signs in the nervous system than mild AD patients, and cranial MRI results showed that mild GPI patients usually had atrophy of the medial temporal lobe. Conclusion: There is an overall decline in cognitive functions of mild GPI patients, which is comparable to that in AD patients, suggesting that there is a wide range of structural changes in the brains of mild GPI patients as well. However, further studies are needed to verify whether these structural changes are similar to those in AD.

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Section: Introductionsupporting

confidence: 91%

Cognitive Impairment in Mild General Paresis of the Insane: AD-Like Pattern

Wang¹,

Guo²,

Zhou

et al. 2011

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

show abstract

“…1 Publikationen mit psychiatrischen Differenzialdiagnosen der Neurosyphilis nach ICD-10. Goeman et al[22]; Fox et al[21]; Lee et al[53]; Mahmoudi et al[54]; Brinar et al[55]; Van Eijsden et al[20]; Blatz et al[27]; Lee et al[56]; Luo et al[57]; Ates et al[58]; Hutto et al[25]; Montejo et al[59]; Russouw et al[28]; Fujimoto et al[60]; Morikawa et al[61]; Xue et al[62]; Timmermans et al[14]; Lessig et al[63]; Gabriel et al[64]; Mehrabian et al[65]; Antonowicz[66]; Yu et al[68]; Polsky et al[69] F0: andere Boerner[70]; Denays et al[71]; Mannekote et al[67]; Blatz et al[27]; Zifko et al[72]; Russouw et al[28]; Mancuso et al[73]; Sobhan et al[74]; Lair et al[75]; Estevez[76]; Sanchez et al[43]; Tibrewal et al[77]; Flood et al[13]; Ilankovic et al[78]; Foatelli et al[79] Abschließend bleibt festzuhalten, dass es bis dato keinen Konsens über den Umgang mit psychiatrischen Manifestationsformen und keine Richtlinien für die Behandlung von psychiatrischen Symptomen im Rahmen der Neurosyphilis gibt[43]. Hier sind Analysen der vorhandenen Daten und prospektive multizentrische Studien wichtig, um in Zukunft die Patienten effektiver behandeln zu können.…”

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