l-norAdrenaline in the Suprarenal Medulla

Calcium‐dependent in vitro interaction between bovine adrenal medullary cell membranes and chromaffin granules as a model for exocytosis

“…Catecholamine concentration was measured by the calorimetric method in [24] with the exception that acetate buffer was replaced by a citrate-phosphate buffer [21].…”

Temperature dependence of catecholamine depletion by reserpine in the heart of the toad (Bufo marinus)

“…The frozen wafers of muscle were quickly ground with a pestle and mortar which had also been precooled with liquid air. The catecholamines were extracted with 0 01 N HCl (Shore & Olin, 1958) and separated by paper chromatography (Euler & Hamberg, 1949). The portions of the chromatogram containing each catecholamine were identified under ultraviolet light.…”

A COMPARISON OF THE EFFECTS OF l-NOR-EPINEPHRINE, SYNTHETIC l-EPINEPHRINE, AND U.S.P. EPINEPHRINE UPON CEREBRAL BLOOD FLOW AND METABOLISM IN MAN 1

“…Since methylation occurs readily in the body, it has been suggested that nor-epinephrine functions chiefly as a precursor to epinephrine (1)(2)(3)(4)(5). Nevertheless, it possesses potent pharmacologic properties which differ in many respects from those of epinephrine (6)(7)(8)(9).…”

“…Because of the similarity of the hemodynamic changes in essential hypertension to those induced experimentally by the administration of l-nor-epinephrine, it has been suggested that i-norepinephrine may play an important role in the pathogenesis of essential hypertension (6). A measure of support for this hypothesis would be gained if nor-epinephrine-induced hypertension 1 Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.…”