Köpeklerde Patellar Luksasyonda Kıkırdak Erozyonunun Prevalansı ve Etkilenmiş Eklemlerdeki Gen Ekspresyonu

Boonsri, Burin; Pradit, Waranee; Soontornvipart, Kumpanart; Yano, Terdsak; Chomdej, Siriwadee; Ongchai, Siriwan; Nganvongpanit, Korakot

doi:10.9775/kvfd.2016.15036

Cited by 2 publications

(4 citation statements)

References 37 publications

(54 reference statements)

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“…There were no pathological findings on the lateral ridge of femoral condyle. In agreement with the previous studies, the most area of eroded cartilage on femoral condyle were found on the medial trochlear ridge performing by gross examination (Alam et al, 2011;Boonsri et al, 2016;Jahrupatrakorn, 2017). Cartilage lesions are subsequently appeared due to the luxation of patella (Daems et al, 2009;Vollnberg et al, 2012).…”

Section: Discussionsupporting

confidence: 91%

Chondroprotective efficacy of pcso-524 on canine osteoarthritis secondary to medial patellar luxation

Sathienbumrungkit

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Fifty stifles from Pomeranians and Chihuahuas with over five years old were enrolled in this study, which are 8 normal stifles and 42 medial patellar luxation (MPL) stifles. All MPL stifles were assigned randomly into 2 groups, including control and treatment groups. The control group was received placebo daily for 16 weeks, while treatment group was fed with PCSO-524 for 16 weeks.�Lameness score, ultrasonographic findings, radiographic OA score and owner questionnaire (cBPI) were assessed at pre-treatment (D0) and post-treatment at week 2, 4, 8, 12 and 16. The ultrasonographic evaluations consisted of synovial fluid, articular cartilage, bone surface and ultrasonographic score. In treatment group, the ultrasonographic, synovial fluid and articular cartilage score of proximo-medial femoral condyle were found a significant improvement after 4 week of treatment. The radiographic OA score was significant improvement after 12 weeks of treatment while lameness score and cBPI�were found a better outcome within 2 weeks. This study revealed that PCSO-524 has an effectiveness of cartilage protection in dogs with OA secondary to MPL. The surgical procedures are remain suggested in order to decreasing progressive OA. However, MPL dogs are recommended for training quadriceps muscle and environmental managements with administration of PCSO-524 for better quality of life.

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Section: Discussionsupporting

confidence: 91%

Chondroprotective efficacy of pcso-524 on canine osteoarthritis secondary to medial patellar luxation

Sathienbumrungkit

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“…In the non-recurrence group, the dates were record from the surgery date to the end of December, 2015. The recurrence rate was compared between the grade of patellar luxation (1)(2)(3)(4), and between the unilateral and the bilateral patellar luxation.…”

Section: Recurrence Ratementioning

confidence: 99%

“…As well documented, in small animal orthopedics, patellar luxation is one of the most common joint diseases in dogs, particularly small breed dogs [1][2][3][4] . Consequence of this disease being left untreated is that it can cause many complications and disorders such as cranial cruciate rupture [1,5] , cartilage erosion [2,6] , and osteoarthritis [7,8] .…”

Section: Introductionmentioning

confidence: 99%

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Düzleşmemiş Femoral Sulkusda Kemik Rekonstruksiyonu Yapılmaksızın Uygulanan Dört Tekniğin Kombine Kullanıldığı Medial Patella Lukzasyon Operasyonu Hakkında Retrospektif Çalışma: 10 Yıllık Periyotta 133 Olgu (2006-2015)

Nganvongpanit¹,

Buddhachat²,

Boonsri³

et al. 2017

Kafkas Univ Vet Fak Derg

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To assess signalment and outcome for dogs surgically treated for non-flattened femoral sulcus medial patellar luxation with combined soft tissue reconstruction techniques, cranial sartorius desmotomy, medial retinacular fascia release, patellar antirotational suture, and fascia lata overlapping, medical records from January 2006 to December 2015 were reviewed. Information obtained from medical records of cases in the study population included breed, age, sex, weight, type of patellar luxation (unilateral or bilateral), grade of patellar luxation, lameness score record, time of last followup, and time of luxation recurrent. The data were analyzed to determine factors influencing outcomes. Twenty-three dogs from 133 presented recurrent patellar luxation. A total of 12 from the 23 recurrent patellar luxation dogs were bilateral (52%) and 11 (48%) were unilateral. The time of recurrence after surgery varied from 1 month to 79 months. From the medical records as on the day of the study, it was found that the longest time that there was no recurrence in dogs was 10 years. It was found that, among the many factors, only grade 4 patellar luxation was a risk factor of considerable recurrence rate (OR=12.44, P=0.02). These results suggest that the combined four soft tissue reconstruction techniques demonstrated excellent outcome in the treatment of medial patellar luxation (with non-flattened femoral sulcus) in small breed dogs. At the same time, it can be stated that bone reconstruction technique is not always necessary. Keywords ÖzetDüzleşmemiş femoral sulkus medial patella lukzasyonu kombine yumuşak doku rekonstrüksiyon teknikleri olan, kranial sartorius desmotomi, medial retinakular fasyanın serbestleştirilmesi, patella antirotasyonal dikiş ve fasia lata üstüste getirme ile tedavi edilen köpeklerin durumlarını ve elde edilen sonuçları değerlendirmek amacıyla, Ocak 2006 ile Aralık 2015 tarihleri arasındaki hasta raporları gözden geçirildi. Çalışmadaki olguların raporlarından elde edilen bilgiler ırk, yaş, cinsiyet, ağırlık, patella lukzasyon tipi (unilateral veya bilateral), patella lukzasyon derecesi, topallık skoru, son takip zamanı ve lukzasyon tekrarlama zamanı bilgilerini içerdi. Sonuçları etkileyen faktörleri belirlemek amacıyla veriler analiz edildi. Toplam 133 köpekten 23'ünde tekrarlayan patella lukzasyonu bulunmaktaydı. Bu olguların 12'si (%52) bilateral ve 11'i (%48) unilateral karakterdeydi. Operasyon sonrası tekrarlama zamanı 1 ay ile 79 ay arasında değişti. Çalışmanın yapıldığı zaman itibariyle tekrarlama görülmeyen en uzun zaman 10 yıl olarak belirlendi. Birçok faktör arasından sadece 4. derece patella lukzasyonu tekrarlama oranı (OR=12.44, P=0.02) için risk faktörü oluşturmaktaydı. Bu sonuçlar kombine olarak dört yumuşak doku rekonstrüksiyon tekniğinin küçük cüsseli köpeklerde medial patella lukzasyon (düzleşmemiş femoral sulkuslu) tedavisinde mükemmel sonuç gösterdiğini belirtmektedir. Ayrıca, kemik rekonstrüksiyon tekniğinin her zaman gerekli olmadığı söylenebilir.

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Köpeklerde Patellar Luksasyonda Kıkırdak Erozyonunun Prevalansı ve Etkilenmiş Eklemlerdeki Gen Ekspresyonu

Cited by 2 publications

References 37 publications

Chondroprotective efficacy of pcso-524 on canine osteoarthritis secondary to medial patellar luxation

Chondroprotective efficacy of pcso-524 on canine osteoarthritis secondary to medial patellar luxation

Düzleşmemiş Femoral Sulkusda Kemik Rekonstruksiyonu Yapılmaksızın Uygulanan Dört Tekniğin Kombine Kullanıldığı Medial Patella Lukzasyon Operasyonu Hakkında Retrospektif Çalışma: 10 Yıllık Periyotta 133 Olgu (2006-2015)

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