Kinetics of the Disappearance of Galactose From the Plasma After a Rapid Intravenous Injection

Abstract

The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.

On the Kinetics of the Elimination of Intravenous Fat Emulsion from the Blood Stream in Dog and Man

“…The elim ination curve described is unusual but not unique as sim ilar curves have been observed for alcohol (Goldberg, 1943), galactos (Dominguerz and Pomerene, 1944) and for sulfobromophthalein (Pagliardi el al., 1963). The fact th a t these circum stances also seem to be valid for such biological substances as triglycerides (both as chylom icrons and as artificial fa t emulsion) makes this ty p e of curve still m ore interesting.…”

Expressing the quantity of urinary analytes: a discussion of some issues arising from the monitoring of the menstrual cycle

“…In (E) the line is the least squares fit to the data (r = 0.999) and both the slope (β 1 = 2.83 ± 0.09 L h -1 [95% CI]) and the intercept (β 0 = -0.2 ± 0.1 g h -1 [95% CI]) are significantly different from zero (p ≤ 0.012). The data are those reported by Dominguez and Pomerene[133].…”

“…The fundamental features of Rehberg's results are not peculiar to humans or to creatinine. Among many possible examples, Figure 2 is a summary of the results obtained from a single experiment in which galactose was injected into a dog at t = 0 h [133]. Both s galactose and J galactose decline exponentially (Figures 2, A and C), but no consistent pattern is apparent for u galactose ( Figure 2B).…”

The Metabolism of D-Ribose in Man

“…Calculations of the above type present the inherent difficulty of estimating the amount present in the body at time zero, the theoretical moment of mixing, as well as the concentration at that time, mainly due to the fact that ribose has a metabolic fate other than simple distribution and excretion. Under these circumstances, a preferable type of calculation is that employed by us for determining the volume of distribution of xylose (16) and based on the theoretical development of Dominguez, Goldblatt, and Pomerene (32,33) and others (34). This treatment requires the constant infusion type of experiment shown in Figures 5 and 6.…”