Kinetic Study of <i>Sasa veitchii</i> Extract as a Radical Scavenger and an Antioxidant

Okada, Youji; Okajima, Hideo; Takeshita, Kazuo; Kanamori, Masato

doi:10.1111/j.1750-3841.2012.02943.x

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…Recently, extracts of bamboo leaves were reported to have multiple biological activities including antioxidant activity and cancer prevention [ 3 , 4 ]. Furthermore, previous studies have demonstrated the antitumor [ 5 ], antioxidant [ 1 , 6 ], antiviral [ 7 ], anti-inflammatory [ 8 ], and anti-allergic [ 9 ] activities of the extract.…”

Section: Introductionmentioning

confidence: 99%

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice

Yoshioka

Usuda

Fujii

et al. 2017

Environ Health Prev Med

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Background: The aim of this study was to investigate the therapeutic effects of a Sasa veitchii leaf extract (SE) on acetaminophen (APAP)-induced hepatotoxicity. Methods: Seven-week-old male ddY mice were orally administered SE or saline (0.2 mL) once a day for a week. Twenty-four hours after the last pretreatment, the mice were intraperitoneally injected with 550 mg/kg APAP or saline under fasting conditions. The mice from each group were euthanized and bled for plasma analysis 2, 6, 24, and 72 h after the injection.

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Section: Introductionmentioning

confidence: 99%

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice

Yoshioka

Usuda

Fujii

et al. 2017

Environ Health Prev Med

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“…The leaves contain lignin, polysaccharides, and chlorophyll, among other components [ 12 , 13 ], and are used as a folk medicine for stomachaches. Recently, Kumazasa extract has been observed to have various pharmacological effects, such as antioxidant [ 14 ], anti-inflammatory [ 15 , 16 ], antibacterial [ 17 , 18 ], and anticancer effects [ 19 ], and to be useful as a health food material. In addition, Kumazasa extract has been reported to have a wound healing effect [ 20 ], and its effect on the skin is also attracting attention.…”

Section: Introductionmentioning

confidence: 99%

Wound-Healing and Skin-Moisturizing Effects of Sasa veitchii Extract

et al. 2021

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Sasa veitchii (S. veitchii) is a traditional herb derived from the bamboo genus, which is collectively called Kumazasa. Although Kumazasa extract is believed to have various effects on the skin, there is little scientific evidence for these effects. In this study, we aimed to obtain scientific evidence regarding the wound-healing and skin-moisturizing effects of Kumazasa extract. Kumazasa extract was applied to the skin of a mouse wound model for 14 days, and the wound area and dermal water content were measured. Mice treated with Kumazasa extract had smaller wound areas than control mice. The dermal water content in the Kumazasa extract-treated group was significantly higher than that in the control group. The mRNA and protein expression levels of cutaneous aquaporin-3 (AQP3), which is involved in wound healing and increases in dermal water content, were significantly increased by treatment with Kumazasa extract. Kumazasa extract-treated HaCaT cells exhibited significantly higher AQP3 expression and p38 mitogen-activated protein kinase (MAPK) phosphorylation than control cells. With continuous application, Kumazasa extract increases AQP3 expression and exerts wound-healing and moisturizing effects. The increase in AQP3 expression elicited by Kumazasa extract may be due to enhancement of transcription via activation of p38 MAPK signaling.

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Protective effects of Sasa veitchii extract on acute ethanol‐induced hepatotoxicity in mice

Yoshioka

Tominaga

Nishikawa

et al. 2020

Traditional & Kampo Medicine

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AimHigh alcohol consumption leads to alcohol‐related disease. The aim of this study was to explore the effects of Sasa veitchii extract (SE) on ethanol‐induced liver injury.MethodsOf four groups of 7‐week‐old male mice (control, SE, ethanol, and SE + ethanol groups), SE and SE + ethanol groups were orally treated with SE once a day for 3 days. Twenty‐four hours after the last administration, the SE + ethanol and ethanol groups were intraperitoneally injected with ethanol (2 g/kg). The mice in each group were euthanized 24 h after ethanol administration, and blood and livers were collected.ResultsHistopathological examination of the livers of ethanol‐treated mice revealed a depletion of glycogen. Ethanol injection resulted in high plasma levels of alanine aminotransferase and aspartate aminotransferase and high levels of hepatic lipid peroxidation and inflammatory cytokines. Pretreatment with SE reversed all these changes in SE + ethanol mice compared to that in the ethanol group. Moreover, SE injection increased the hepatic protein levels of aldehyde dehydrogenase 2.ConclusionOur results show that SE protected the mice against acute ethanol‐induced hepatic injury by modulating oxidative stress and ethanol metabolism, and hence, could be explored for treatment of alcohol‐related disease.

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Kinetic Study of Sasa veitchii Extract as a Radical Scavenger and an Antioxidant

Abstract: We determined the stoichiometric number and the rate constants of bamboo extracts using the method that was devised in determining the antioxidant activity of mixtures. This is the first study of bamboo extracts as an antioxidant that reports the stoichiometric and kinetic results.

Cited by 6 publications

References 24 publications

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice

Wound-Healing and Skin-Moisturizing Effects of Sasa veitchii Extract

Protective effects of Sasa veitchii extract on acute ethanol‐induced hepatotoxicity in mice

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