Kimura’s Disease

Deshpande, Archana; Nayak, Supreeta; Munshi, Maitreyee; Bobhate, S. K.

doi:10.1159/000326734

Cited by 40 publications

(14 citation statements)

References 15 publications

(37 reference statements)

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“…Although there is no specific diagnostic feature of Kimura disease, FNA is helpful in preoperative diagnosis of Kimura’s disease. Smears show significant numbers of eosinophils in a background of lymphoid cells with occasional fragments of collagenous tissue and Warthin-Finkeldey polykaryocytes [11]. In our case of FNA smears revealed polymorphous population of lymphoid cells, histiocytes and endothelial cell clusters in the background of abundant eosinophils, lymphohistiocytes, fibrous stroma and hemorrhage.…”

Section: Discussionmentioning

confidence: 57%

Kimura Disease : Case Report and Brief Review of Literature

Dhingra

Nagpal

Baliyan

et al. 2018

Medicine and Pharmacy Reports

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Kimura disease is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling, blood and tissue eosinophilia and raised IgE levels. Early diagnosis of Kimura’s disease may spare the patient from unnecessary invasive diagnostic procedure. We describe a case of Kimura disease in a 14-year old male presenting with left submandibular swelling and also provide a brief review of the literature.

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Section: Discussionmentioning

confidence: 57%

Kimura Disease : Case Report and Brief Review of Literature

Dhingra

Nagpal

Baliyan

et al. 2018

Medicine and Pharmacy Reports

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“…Some authors were able to diagnose Kimura’s disease on FNAC [ 13 ], whereas others have reported the swellings as lymphadenitis or malignancies [ 14 , 15 ]. The characteristic features of Kimura’s disease on FNAC are the presence of significant numbers of eosinophils in a background of lymphoid cells, with fragments of collagenous tissue, endothelial cells and occasional polykaryocytes [ 14 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

“…Marked vascular hyperplasia and fibrosis are also present. No atypical cells are observed [ 13–15 ].…”

Section: Discussionmentioning

confidence: 99%

“…Surgery has been considered as the gold standard treatment modality. In cases where the disease involves the subcutaneous tissue without well-defined margins, a combination of surgery with postoperative systemic corticosteroids and low-dose radiotherapy have been recommended [ 12 , 13 ], as recurrence rate of up to 62% have been reported in these cases with surgery alone [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

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Kimura’s disease: a rare cause of chronic neck lymphadenopathy

Kok

Lim

2021

Journal of Surgical Case Reports

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Kimura’s disease is a rare chronic inflammatory disorder of unknown etiology which typically presents with subcutaneous nodules in the head and neck region and is frequently associated with regional lymphadenopathy or salivary gland enlargement. Peripheral blood eosinophilia and elevated serum immunoglobulin E levels are constant features of the disease. We present herein a 31-year-old male patient who presented with chronic neck lymphadenopathy. Kimura’s disease was diagnosed on fine needle aspiration cytology, the patient initially decided not to have further intervention. He presented 6 years later with lymphadenopathy and was treated with surgery. The diagnosis of Kimura’s disease was confirmed on histopathology. This patient had the disease for 6 years and did not have the typical features of peripheral eosinophilia and raise serum IgE level.

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“…Few of the studies have highlighted certain characteristic features in fine needle aspiration smears that are helpful in preoperative diagnosis of Kimura's disease;[678] these are, the presence of significant numbers of eosinophils in a background of lymphoid cells with occasional fragments of collagenous tissue and Warthin-Finkeldey polykaryocytes. The cytologic features of this disease have to be interpreted in the appropriate clinical setting in order to make a correct preoperative diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Kimura's disease: A diagnostic challenge experienced with cytology of postauricular swelling with histopathological relevance

Sherpa

Lamichaney

Roy

2016

J Cytol

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Kimura's disease is a rare, chronic inflammatory disorder of unknown cause. It is endemic in Asia, affecting more number of males than females, with a ratio of 3:1. The typical clinical manifestations include a triad of painless unilateral cervical lymphadenopathy or subcutaneous masses predominantly in the head and neck region, blood and tissue eosinophilia, and an elevated serum immunoglobulin E (IgE) levels. Variable conditions both benign and malignant may mimic Kimura's disease both clinically and on fine needle aspirates. The confirmatory diagnosis is established only by histopathological examination. We report a case of Kimura's disease in a patient who underwent multiple investigations in view of her past history and family history of pulmonary Koch's. Fine needle aspiration cytology (FNAC) was performed thrice with consistently similar result of reactive lymphadenitis with numerous histiocytes and eosinophilia. The final diagnosis of Kimura's disease could finally be established only on histopathological examination.

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Kimura’s Disease

Cited by 40 publications

References 15 publications

Kimura Disease : Case Report and Brief Review of Literature

Kimura Disease : Case Report and Brief Review of Literature

Kimura’s disease: a rare cause of chronic neck lymphadenopathy

Kimura's disease: A diagnostic challenge experienced with cytology of postauricular swelling with histopathological relevance

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